Roman Jerala - Selected Publications#

1. Pohar J., Lainšček D., Ivičak-Kocjan K., Cajnko M., Jerala, R*, Benčina, M. (2017) Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9. Nature Commun. (in press) *shared senior author

2. Kočar V., Schreck JS, Čeru S, Gradišar H, Bašić N, Pisanski T., Doye J.P., Jerala R. (2016) Design principles for rapid folding of knotted DNA nanostructures. Nature Commun. 18; 7:10803.

3. Gradišar, H., Božič, S., Doles, T., Vengust, D., Hafner Bratkovič, I., Mertelj, A., Webb, B., Šali, A., Klavžar, S., Jerala, R. (2013). Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments. Nature chemical biology, 9, 362-366

4. Gaber, R., Lebar, T., Majerle, A., Šter, B., Dobnikar, A., Benčina, M., Jerala, R. (2014) Designable DNA-binding domains enable construction of logic circuits in mammalian cells. Nature chemical biology, 10, 203-208.

5. Lebar, T. Bezeljak, U., Golob, A., Jerala, M., Kadunc, L., Pirš., B., Stražar, M., Vučko, D., Zupančič, U., Benčina, M., Forstnerič, V., Gaber, R., Lonzarić, J., Majerle, A., Oblak, A., Smole, A. & Jerala, R. (2014) A bistable genetic switch based on designable DNA-binding domains. Nature Commun. 5:5007 doi: 10.1038/ncomms6007.

6. Conrado RJ, Wu GC, Boock JT, Xu H, Chen SY, Lebar T, Turnšek J, Tomšič N, Avbelj M, Gaber R, Koprivnjak T, Mori J, Glavnik V, Vovk I, Benčina M, Hodnik V, Anderluh G, Dueber JE, Jerala R*, DeLisa MP (2012) DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic acids research, 40, 1879-1889. *shared senior author, cited 52 times.

7. Pirher N, Ivičak K, Pohar J, Benčina M, Jerala R. (2008) A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation. Nature Struct Mol Biol., 15, 761-763.

8. Avbelj M, Wolz OO, Fekonja O, Benčina M, Repič M, Mavri J, Krüger J, Schärfe C, Delmiro Garcia M, Panter G, Kohlbacher O, Weber AN, Jerala R. (2014) Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization. Blood. 124(26):3896-904.

9. Manček-Keber M, Frank-Bertoncelj M, Hafner-Bratkovič I, Smole A, Zorko M, Pirher N, Hayer S, Kralj-Iglič V, Rozman B, Ilc N, Horvat S, Jerala R (2015) Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles. Science Signal 16, (381) ra60.

10. Kužnik, A., Benčina, M., Švajger, U., Jeras, M., Rozman, B., Jerala, R. (2011). Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines. The journal of immunology, 186, 4794-8408 (196 citations)