Thanos Halazonetis Selected Publications#

Macheret, Halazonetis. (2018). Intragenic origins due to short G1 phases underlie oncogene−induced DNA replication stress. Nature 555, 112−116.

Costantino, Sotiriou, Rantala, Magin, Mladenov, Helleday, Haber, Iliakis, Kallioniemi, Halazonetis. (2014). Break−induced replication repair of damaged forks induces genomic duplications in human cells. Science 343, 88−91.

Negrini, Gorgoulis, Halazonetis. (2010). Genomic instability − an evolving hallmark of cancer. Nature Reviews Molecular Cell Biology 11, 220−228.

Halazonetis, Gorgoulis, Bartek. (2008). An oncogene−induced DNA damage model for cancer development. Science 319, 1352−1355.

Bartkova, Rezaei, Liontos, Karakaidos, Kletsas, Issaeva, Vassiliou, Kolettas, Niforou, Zoumpourlis, Takaoka, Nakagawa, Tort, Fugger, Johansson, Sehested, Andersen, Dyrskjot, Orntoft, Lukas, Kittas, Helleday, Halazonetis, Bartek, Gorgoulis. (2006). Oncogene− induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444, 633−637.

Gorgoulis , Vassiliou, Karakaidos, Zacharatos, Kotsinas, Liloglou, Venere, DiTullio, Kastrinakis, Levy, Kletsas, Yoneta, Herlyn, Kittas, Halazonetis. (2005). Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434, 907−913.

Huyen, Zgheib, DiTullio, Gorgoulis, Zacharatos, Petty, Sheston, Mellert, Stavridi, Halazonetis. (2004). Methylated lysine 79 of histone H3 targets 53BP1 to DNA double−strand breaks. Nature 432, 406−411.

Chehab, Malikzay, Appel, Halazonetis. (2000). Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53. Genes Dev. 14, 278−288.

Schultz, Chehab, Malikzay, Halazonetis. (2000). 53BP1 is an early participant in the cellular response to DNA double−strand breaks. J. Cell Biol. 151, 1381−1390.

Halazonetis, Georgopoulos, Greenberg, Leder. (1988). c−Jun dimerizes with itself and with c−Fos, forming complexes of different DNA binding affinities. Cell 55, 917−924.