Partial List of Publications#
Labuschagne CF, van den Broek NJ, Macjay GM, Vousden KH* and Maddocks OD. Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells. Cell Rep. 7:1248-1258, 2014
Trinidad AG, Muller PA, Cuellar J, Klejnot M, Nobis M, Valpuesta JM, Vousden KH. Interaction of p53 with the CCT complex promoted protein folding and wild type p53 activity. Mol Cell 50:805-817 2013
Cheung E, Athineos D, Lee P, Ridgeway R, Lambie W, Nixon C, Strathdee D, Blyth K, Sansom O, Vousden KH. TIGAR is required for efficient intestinal regeneration and tumorigensis. Dev Cell 25:463-477, 2013
Maddocks ODK, Berkers CR, Mason SM, Zheng L, Blyth K, Gottlieb E, Vousden KH. Serine starvation induces stress and p53 dependent metabolic remodeling in cancer cells. Nature, 493: 542-546, 2013
Eric C. Cheung, Robert L. Ludwig and Karen H. Vousden. Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death. PNAS, 109: 20491-20496, 2012
Rainero E, Caswell, PT, Muller PAJ, Grindlay J, McCaffery MW, Zhang Q, Wakelam MJO, Vousden KH, Grazuani A, Norman JC. Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration. J Cell Biol, 196:277-295, 2012
Dou H, Buetow L, Hock A, Sibbet GJ, Vousden KH and Huang DT. Strutural basis for autoinhibition and phosphorylation dependent activation of c-Cbl. Nature Struct. Mol. Biol. 19:184-192, 2012
Chaneton B, Hillmann P, Zheng L, Martin ACL, Maddocks ODK, Chokkathukalam A, Coyle JE, Jankevics A, Holding FP, Vousden KH, Frezza C, O’Reilly M, Gottlieb E. Serine is a natural ligand and allosteric activator of pyruvate kinase M1. Nature 491: 458-462, 2012
Vigneron AM, Ludwig RL and Vousden KH Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP. Genes & Dev, 24:2430-2439, 2010
Muller PAJ, Caswell PT, Doyle B, Iwanicki MP, Tan EH, Karim S, Lukashchuk N, Gillespie DA, Ludwig RL, Gosselin P, Cromer A, Brugge JS, Sansom OJ, Norman JC, Vousden KH. Mutant p53 drives invasion by promoting integrin recycling. Cell 139: 1327-1341, 2009.
Bensaad K, Cheung EC and Vousden KH. Modulation of intracellular ROS levels by TIGAR controls autophagy. EMBO J. 28: 3015-3026, 2009
Total of 270 publications, average citations per article 105, h-index 85
