Stephen Taylor - Major publications#

l. Taylor, S. S. and McKeon, F. (1997). Kinetochore localization of murine Bubl is required for normal mitotic timing and checkpoint response to spindle damage. Cell 89, 727-35.

2. Taylor, S. S., Hussein, D., Wang, Y., Elderkin, S. & Morrow, CJ. Kinetochore localisation and phosphorylation ofthe mitotic checkpoint components Bubl and BubR1 are differentially regulated by spindle events in human cells. J Cell Sci 114, 4385-95 (2001).

3. Ditchtield, C., Johnson, V. L., Tighe, A., Ellston, R., Haworth, C., Johnson, T., Mortlock, A., Keen, N. & Taylor, S. S. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 161, 267-80 (2003).
Ditchfield at al (2003) is the most highly cited J Cell Biol paper for that year.

4. Keen, N. and Taylor, S. (2004). Aurora-kinase inhibitors as anticancer agents. Nat Rev Cancer 4, 927-36.

5. Girdler, F., K. Gascoigne, P.A. Eyers, K. Foote, C. Crafter, N. Keen, and Taylor, S. S. (2006) Validating Aurora B as an anti-cancer agent. J Cell Sci 119, 3664-75.

6. Vergnolle, M.A., and Taylor, S.S. (2007). Cenp-F links kinetochores to Ndell/Ndel/Lisl/dynein microtubule motor complexes. Curr Biol 17, 1 173-1 179.

7. Perera, D., Tilston, V., Hopwood, J.A., Barchi, M., Boot-Handford, R.P., and Taylor, S.S. (2007). Bubl maintains centromeric cohesion by activation of the spindle checkpoint. Dev Cell 13, 566-579.

8. Tighe, A., Staples, O.D., and Taylor, S.S. (2008). Mpsl kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores, J Cell Biol 181, 893-901.

9. Girdler, F., Sessa, S., Patercoli, S., Villa, F., Musacchio, A., and Taylor, S. S. (2008) Molecular basis of drug-resistance in Aurora kinases. Chemistry & Biology 15, 552-562.

10. Gascoigne, K. and Taylor, S.S. (2008) Cancer cells display profound intra- and interline variation following prolonged exposure to anti-mitotic drugs. Cancer Cell 14, 111-122.
Gascoigne & Taylor (2008) was Cancer Cell’s Featured Article, i.e, the editors selected it for open access and the cover image. lt was thejournals most highly downloaded article in August 2008. A video interview was distributed by BSN News, and a radio interview broadcast by BBC World Service "Health Matters" (Ol/09/08). The paper was also previewed by Holland, A.J. and Cleveland, D.W, (2008) Beyond genetics: surprising determinants of cell fate in antitumor drugs Cancer Cell 14, 103-5.