Iannis Talianidis - Selected publications#

Nikolaou KC., Moulos P., Harokopos V., Chalepakis G., Talianidis I. (2017) Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions. Cell Rep. 20: 909-922

Giakountis A., Moulos P., Sarris ME., Hatzis P., Talianidis I. (2017) Smyd3-associated regulatory pathways in cancer. Semin Cancer Biol. 42:654-663.

Elkouris M, Kontaki H, Stavropoulos A, Anastasia Antonoglou A, Nikolaou KC, Samiotaki M, Szantai E, Brown PJ, Sideras P, Panayotou G, Talianidis I. (2016) SET9-mediated regulation of TGF-b signaling links protein methylation to pulmonary fibrosis. Cell Rep. 15:2733-2744.

Sarris ME, Moulos P, Haroniti A, Giakountis A, Talianidis I. (2016) Smyd3 is a transcriptional potentiator of multiple cancer-promoting genes and required for liver and colon cancer development. Cancer Cell 29:354-366.

Nikolaou KC, Moulos P, Chalepakis G, Hatzis P, Oda H, Reinberg D, Talianidis I. (2015) Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 34:430-447.

Stefflova K., Thyber D., Wilson MD., Streeter I., Aleksic J., Karagianni P., Brazma A., Adams DJ., Talianidis I., Marioni JC., Flicek P., Odom DT. (2013) Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals. Cell 154:530-540.

Nikolaou K, Sarris M, Talianidis I. (2013) Molecular pathways: the complex roles of inflammation pathways in the development and treatment of liver cancer. Clin Cancer Res. 19:2810-2816.

Nikolaou K., Tsagaratou A., Eftychi C., Kollias G., Mosialos G., Talianidis I. (2012) Inactivation of the deubiquitinase CYLD in hepatocytes causes apoptosis, inflammation, fibrosis and cancer. Cancer Cell 21:738-750

Kamileri I., Karakasilioti I., Sideri A., Kosteas T., Tatarakis A., Talianidis I, Garinis GA. (2012) Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc. Natl. Acad. Sci. U S A 109:2995-3000.

Kontaki H., Talianidis I. (2010) Lysine methylation regulates E2F1-induced cell death. Mol. Cell 39:152-160.

Schmidt D, Wilson MD, Ballester B, Schwalie PC, Brown GD, Marshall A, Kutter C, Watt S, Martinez-Jimenez CP, Mackay S, Talianidis I, Flicek P, Odom DT. (2010) Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding. Science 328:1036-1040.

Martinez-Jimenez CP, Kyrmizi I, Cardot P, Gonzalez FJ, Talianidis I. (2010) Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism. Mol Cell Biol. 30:565-577.

Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I. (2008) Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell. 31:531-543.

Sanyal S, Bavner A, Haroniti A, Nilsson LM, Lundasen T, Rehnmark S, Witt MR, Einarsson C, Talianidis I, Gustafsson JA, Treuter E. (2007) Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis. Proc. Natl. Acad. Sci. U S A 104:15665-15670.

Kyrmizi, I., Hatzis, P., Katrakili, N., Tronche, F., Gonzalez, FJ. and Talianidis I. (2006) Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 20:2293-2305.