Anna Moroni - Selected Publications#

1. Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A. (2021) Gating movements and ion permeation in HCN4 pacemaker channels. Mol Cell. 81(14):2929-2943.e6.

2. Porro A, Saponaro A, Gasparri F, Bauer D, Gross C, Pisoni M, Abbandonato G, Hamacher K, Santoro B, Thiel G, Moroni A. (2019) The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels. Elife. 8:e49672.

3. Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A. (2018) A light-gated potassium channel for sustained neuronal inhibition. Nat Methods. 15(11):969-976

4.Saponaro A, Porro A, Chaves-Sanjuan A, Nardini M, Rauh O, Thiel G, Moroni A. (2017) Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell 2017 29(10):2570-2580.

5. Cosentino C, Alberio L, Gazzarrini S, Aquila M, Romano E, Cermenati S, Zuccolini P, Petersen J, Beltrame M, Van Etten JL, Christie JM, Thiel G, Moroni A. (2015) Engineering of a light-gated potassium channel. Science 348(6235):707-10.

6. Lolicato, M., Bucchi, A., Arrigoni, C., Zucca, S., Nardini, M., Schroeder, I., Simmons, K., Aquila, M., DiFrancesco, D., Bolognesi, M., Schwede, F., Kashin, D., Fishwick, C.W.G, Johnson, A.P., Thiel, G., Moroni, A. (2014) Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat Chem Biol. 10(6):457-62.

7. Saponaro A, Pauleta SR, Cantini F, Matzapetakis M, Hammann C, Donadoni C, Hu L, Thiel G, Banci L, Santoro B, Moroni A. (2014) Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proc Natl Acad Sci U S A. 111(40):14577-82.

8. Moroni, A, Thiel, G (2006). Flip-flopping salt bridges gate an ion channel. Nature Chemical Biology, vol. 2, p. 572-573.

9. Gazzarrini, S,Kang, M, Epimashko, S., Van Etten, J. L., Dainty, J, Thiel, G, Moroni , A (2006). Chlorella virus MT325 encodes water and potassium channels that interact synergistically. Proc Natl Acad Sci U S A. 103, p. 5355-5360.

10. Plugge B, Gazzarrini S, Nelson M, Cerana R, Van Etten JL, Derst C, DiFrancesco D, Moroni A, Thiel G. (2000) A new potassium channel protein encoded by Chlorella virus PBCV-1. Science, Volume 287, 1641-1644.