Jean-Louis Mergny - Selected Publications#

226 articles currently listed in Web of Science and 15 patents. Nucleic Acids Res., Angewandte Chemie, JACS, ACS Nano, ACS Catalysis, Nano Letters, Nature Chem. Biol., Nature Medicine, Acc. Chem. Res., Chem. Rev. and Science. 9 articles have been recommended by Faculty of 1000; 5 are currently "Highly cited" (Top 1%) according to Web of Science. 76 articles have been published during the last 5 years.

Over 13,400 citations (h-index = 64) according to Web of Science (18300 citations and h=76 according to Google Scholar).

10 selected recent papers (2014-2019):

1. Mergny JL*, Sen D. DNA Quadruple Helices in Nanotechnology. Chem. Rev. 2019, in press doi: 10.1021/acs.chemrev.8b00629.

2. Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, Draskovic I, Londoño-Vallejo JA, Dupuy JW, Das RN, Robert G, Orange F, Guédin A, Corce F, Velasco V, Soubeyran PL, Ryan K, Mergny JL*, Mergny-Djaveheri M. Modulation of the ATM/Autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells. Nucleic Acids Res. 2019 47: in press.

3. Dzatko S, Krafcikova M, Korkut DN, Hänsel-Hertsch R, Fessl T, Fiala R, Loja T, Mergny JL, Foldynova-Trantirkova S, Trantirek L. Evaluation of stability of DNA i-motifs in the nuclei of living mammalian cells. Angew Chem Int Ed Engl. 2018; 57(8): 2165-2169.

4. Zhou J, Amrane S, Rosu F, Salgado GF, Bian Y, Tateishi-Karimata H, Largy E, Korkut DN, Bourdoncle A, Miyoshi D, Zhang J, Ju H, Wang W, Sugimoto N, Gabelica V, Mergny JL. Unexpected Position-dependent Effects of Ribose G-quartets in G-quadruplexes J Am Chem Soc. 2017; 139: 7768-7779.

5. Bedrat A, Lacroix L, Mergny JL. Re-evaluation of G-quadruplex propensity with G4Hunter. Nucleic Acids Res. 2016; 44:1746-59. (IF2017 = 11.561) Cited over 75 times & Recommended by Faculty of 1000.

6. Largy E, Marchand A, Amrane S, Gabelica V, Mergny JL. Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches. J Am Chem Soc. 2016; 138:2780-92. Featured article

7. Mendoza O, Gueddouda NM, Boulé JB, Bourdoncle A, Mergny JL. A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands. Nucleic Acids Res. 2015 Jun 23;43(11):e71.

8. Salgado GF, Cazenave C, Kerkour A, Mergny JL. G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy. Chem Sci. 2015 vol. 6(6): 3314-3320. Edge Article, Front Cover.

9. Amrane S, Kerkour A, Bedrat A, Vialet B, Andreola ML, Mergny JL. Topology of a DNA G-quadruplex structure formed in the HIV-1 promoter: a potential target for anti-HIV drug development. J Am Chem Soc. 2014 Apr 9;136(14):5249-52.

10. Largy E, Mergny JL. Shape matters: size-exclusion HPLC for the study of nucleic acid structural polymorphism. Nucleic Acids Res. 2014 Oct 29;42(19):e149.