Bengt Mannervik - Selected Publications#

Google scholar h-index 86 (45,106 citations, i10-index 385)

1. Segura-Aguilar J, Muñoz P, Inzunza J, Varshney M, Nalvarte I, Mannervik B. Neuroprotection against Aminochrome Neurotoxicity: Glutathione Transferase M2-2 and DT-Diaphorase. Antioxidants (Basel). 2022;11(2):296. Published 2022 Jan 31. doi:10.3390/antiox11020296

2. Mannervik B, Ismail A, Lindström H, Sjödin B, Ing NH. Glutathione Transferases as Efficient Ketosteroid Isomerases. Front Mol Biosci. 2021;8:765970. Published 2021 Nov 22. doi:10.3389/fmolb.2021.765970

3. Sjödin B, Mannervik B. Role of human glutathione transferases in biotransformation of the nitric oxide prodrug JS-K. Sci Rep. 2021;11(1):20765. Published 2021 Oct 21. doi:10.1038/s41598-021-00327-1

4. Škerlová J, Lindström H, Gonis E, et al. Structure and steroid isomerase activity of Drosophila glutathione transferase E14 essential for ecdysteroid biosynthesis. FEBS Lett. 2020;594(7):1187-1195. doi:10.1002/1873-3468.13718

5. Musdal Y, Govindarajan S, Mannervik B. Exploring sequence-function space of a poplar glutathione transferase using designed information-rich gene variants. Protein Eng Des Sel. 2017;30(8):543-549. doi:10.1093/protein/gzx045

6. Emrén LO, Kurtovic S, Runarsdottir A, Larsson AK, Mannervik B. Functionally diverging molecular quasi-species evolve by crossing two enzymes. Proc Natl Acad Sci U S A. 2006;103(29):10866-10870. doi:10.1073/pnas.0604030103

7. Norrgård MA, Ivarsson Y, Tars K, Mannervik B. Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution. Proc Natl Acad Sci U S A. 2006;103(13):4876-4881. doi:10.1073/pnas.0600849103

8. Berhane K, Widersten M, Engström A, Kozarich JW, Mannervik B. Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc Natl Acad Sci U S A. 1994;91(4):1480-1484. doi:10.1073/pnas.91.4.1480

9. Mannervik B, Ålin P, Guthenberg C, et al. Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A. 1985;82(21):7202-7206. doi:10.1073/pnas.82.21.7202

10. Josephy PD, Mannervik B. Molecular Toxicology, 2nd Ed, Oxford University Press, New York, 2006, 589 pages