Michaela Müller-Trutwin - Selected Publications#

Huot N, Planchais C, Rosenbaum P, Contreras V, Jacquelin B, Petitdemange C, Lazzerini M, Beaumont E, Orta-Resendiz A, Rey F, Reeves RK, Le Grand R, Mouquet H & MC Müller-Trutwin. Regulation by IFN-g and NK cells of SARS-CoV-2 viral persistence in alveolar macrophages of the lung. Nat Immunol. 2023 Dec;24(12):2068-2079. doi: 10.1038/s41590-023-01661-4..

Jost S, O Lucar, T Yoder, K Kroll, S Sugawara, S Smith, R Jones, G Tweet, A Werner, PJ. Tomezsko, HL. Dugan, J Ghofrani, Ph Rascle, M Altfeld, A Grundhoff, M Muller-Trutwin, P Goepfert, R.K Reeves. Human antigen-specific memory natural killer cell responses develop against HIV-1 and influenza virus and are dependent on MHC-E restriction. Science Immunol. 2023 Dec 8;8(90):eadi3974. doi: 10.1126/sciimmunol.adi3974.

Federico Perdomo-Celis, Caroline Passaes, Valérie Monceaux, Stevenn Volant, Faroudy Boufassa, Pierre de Truchis, Morgane Marcou, Katia Bourdic, Laurence Weiss, Corinne Jung, Christine Bourgeois, Cecile Goujard, Laurence Meyer, Michaela Müller-Trutwin, Olivier Lambotte and Asier Sáez-Cirión. Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control. J Clin Invest. 2022 Apr 5:e157549. doi: 10.1172/JCI157549.

Rascle P, Planchais C, Jacquelin B, Lazzerini M, Contreras V, Passaes C, Saez-Cirion A, Mouquet H, Huot N, Müller-Trutwin M. NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections. Commun Biol. 2022;5(1):674. doi: 10.1038/s42003-022-03619-y. PMID: 35798936 .

Huot N, Rascle P, Petitdemange C, Contreras V, Stürzel CM, Baquero E, Harper JL, Passaes C, Legendre R, Varet H, Madec, Sauermann, Stahl-Hennig, Nattermann, Saez-Cirion, Le Grand R, Reeves RK, Paiardini M, Kirchhoff F, Jacquelin B & Müller-Trutwin M. SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity. Nature Communications. 2021;12(1):1282.

Harper J*, Huot N*, Micci L, Tharp G, King C, Rascle P, Shenvi N, Wang H, Galardi C, Upadhyay AA, Villinger F, Lifson J, Silvestri G, Easley K, Jacquelin B, Bosinger S, Müller-Trutwin M* & Paiardini M*. IL-21 and IFN-a therapy rescues the terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques. Nature Communications. 2021;12(1):2866.

Angin M, S Volant, Passaes C, C Lecuroux, V Monceaux, MA Dillies, JC Valle Casuso, Pancino P, Vaslin B, Le Grand R, Weiss L, Goujard C, Meyer L, F Boufassa, M Muller-Trutwin, O Lambotte, A Sáez-Cirión. Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection. Nature Metabolism. 2019 ; (1) 704–716.

Huot N, Jacquelin B, Garcia-Tellez T, Rascle P, Ploquin M, Madec Y, Reeves RK, Derreudre-Bosquet N & Müller-Trutwin M. NK cells migrate into and control SIV replication in lymph node follicles in African green monkeys. Nature Medicine. 2017 Nov;23(11):1277-1286.

Svardal H, Jasinska A; Apetrei C; Coppola G; Jacquelin B; Müller-Trutwin M; Weinstock G, Wilson RK, Warren WC; Freimer NB & Nordborg. Polygenic adaptation to simian immunodeficiency virus across vervet monkey populations. Nature Genetics, 2017;49(12):1705-1713. doi: 10.1038/ng.3980

Jacquelin B., Mayau V, Targat B, Liovat AS, Kunkel D, Petitjean G, Dillies MA, Roques P, Butor C, Giavedoni LD, Lebon P, Barré-Sinoussi F, Benecke A & Müller-Trutwin M. Strong but Rapidly Controlled Interferon Type I Response in Nonpathogenic SIV Infection of African Green Monkeys. J. Clin. Invest. 2009; 119(12):3544-55.