Roger D. Kornberg - Selected Publications#

Kornberg, R.D. (1974) Chromatin structure: A repeating unit of histones and DNA. Science 184, 868-871.

Uzgiris, E.E., and Kornberg, R.D. (1983) Two-dimensional crystallization technique for imaging macromolecules, with an application to antigen-antibody-complement complexes. Nature 301, 125-129.

Kim, Y.J., Bjorklund, S., Li, Y., Sayre, M.H., and Kornberg, R.D. (1994) A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77, 599-608.

Cairns, B.R., Lorch, Y., Li, Y., Zhang, M., Lacomis, L., Erdjument-Bromage, H., Tempst, P., Laurent, B., Kornberg, R.D. (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87, 1249-1260.

Asturias, F.J., Jiang, Y.W., Myers, L.C., Gustafsson, C.M., and Kornberg, R.D. (1999). Conserved structures of Mediator and RNA Polymerase II holoenzyme. Science 283, 985-987.

Cramer, P., Bushnell, D.A., Fu, J., Gnatt, A.L., Maier-Davis, B., Thompson, N.E., Burgess, R.R., Edwards, A.M., David, P.R., and Kornberg, R.D. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288, 640-649.

Cramer, P., Bushnell, D.A., and Kornberg, R.D. (2001) Structural basis of transcription: RNA polymerase II at 2.8 Ångstrom resolution. Science 292, 1863 1876.

Gnatt, A.L., Cramer, P., Fu, J., Bushnell. D.A., and Kornberg, R.D. (2001) Structural basis of transcription: An RNA polymerase II elongation complex at 3.3 Å resolution. Science 292, 1876-1882.

Wang, D., Bushnell, D.A., Westover, K.D., Kaplan, C.D., and Kornberg, R.D. (2006) Structural basis of transcription: Role of the trigger loop in substrate specificity and catalysis. Cell 127:941-954.

Liu, X., Bushnell, D.A., Wang, D., Calero, G., and Kornberg, R.D. (2010) Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science 327:206-209