Charles R.G. Guttmann - Biography#
Dr. Charles R. G. Guttmann is an Associate Professor of Radiology at Harvard Medical School, and the Director of the Center for Neurological Imaging, a multi-disciplinary laboratory at Brigham and Women’s Hospital, combining biomedical and computer scientists/biomedical engineers. Dr. Guttmann graduated from the University of Zurich with a medical degree in 1987 (MD Thesis 1990) and completed a post-graduate course for experimental medicine and biology at the same Institution. His research interests focus on the understanding, modeling, and monitoring of neurological diseases, such as multiple sclerosis (MS) and small vessel disease in aging, by integrating imaging-derived biomarkers with clinical, genetic, immunological, and other biomarkers. To this end his laboratory has developed a large scale repository and image analysis workflow management system that has been in use for over 20 years, and has been populated with images, image-derived metrics, a variety of genetic and blood biomarkers, as well as clinical information obtained inserted at the time of clinical visits. The data repository includes over 25,000 magnetic resonance imaging (MRI) exams. This system has enabled multiple large-scale, cross-disciplinary studies addressing a variety of scientific questions, such as genetic determinants of brain atrophy in MS, association studies between risk factors such as smoking and the progression of disease in MS, as well as prospective longitudinal studies to understand the clinical evolution and pathogenesis of MS.
More recently, Dr. Guttmann and his team have developed SPINE (Structured Planning and Implementation of New Experiments), which is used for collaborative scientific projects, as well as citizen science events.
Dr. Guttmann has published over 180 full-length, peer-reviewed original articles, has received multiple research grants as principal investigator or co-investigator, and has served as reviewer for scientific granting agencies and international scientific journals.
Web of Science SCI h- index: 56; Google Scholar h-index: 71.
See also:
https://connects.catalyst.harvard.edu/Profiles/display/Person/49315
https://scholar.google.com/citations?hl=en&user=YGin91kAAAAJ
https://cni.bwh.harvard.edu
