Stefano Gianni - Selected Publications#
1) Gianni S, McCully ME, Malagrinò F, Bonetti D, De Simone A, Brunori M, Daggett V. (2018) A Carboxylate to Amide Substitution That Switches Protein Folds. Angew Chem Int Ed Engl. 2018 57:12795-12798.
2) Gianni S, Jemth P. (2017) How Fast Is Protein-Ligand Association? Trends Biochem Sci. 42, 847-849.
3) Gianni, S., Dogan, J., Jemth, P. (2016) Coupled binding and folding of intrinsically disordered proteins: what can we learn from kinetics? Curr. Opin. Struct. Biol. 38, 18-24.
4) Di Silvio, E., Brunori, M., Gianni, S. † (2015) Frustration Scuplts the early stages of protein folding Angew Chem Int Ed Engl 54, 10867-10869.
5) Gianni, S. , Camilloni, C., Giri, R., Toto, A., Bonetti, D., Morrone, A., Sormanni, P, Brunori, M., Vendruscolo, M. (2014) Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein. Proc. Natl. Acad. Sci. USA 111, 14141-14146
6) Giri R, Morrone A, Toto A, Brunori M, Gianni, S. (2013) Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system. Proc Natl Acad Sci U S A. 110, 149422-149427
7) Eildal JN, Hultqvist G, Balle T, Stuhr-Hansen N, Padrah S, Gianni S, Strømgaard K, Jemth P. (2013) Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations J. Am. Chem. Soc. 135, 12998-13007
8) Giri., R., Morrone, A., Travaglini-Allocatelli C., Jemth, P., Brunori, M., Gianni, S., (2012) The folding pathways of proteins with increasing degree of sequence identities but different structure and function. Proc. Natl. Acad. Sci. USA. 109, 17772-17776.
9) Haq SR, Chi CN, Bach A, Dogan J, Engström A, Hultqvist G, Karlsson A, Lundström P, Montemiglio LC, Strømgaard K, Gianni S, Jemth P. (2011) Side chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. J. Am. Chem. Soc. 134, 599-605
10) Gianni, S., Ivarsson, Y., De Simone, A., Travaglini-Allocatelli, C., Brunori, M., Vendruscolo M., (2010) Characterization of the Structure of a Misfolded Intermediate Populated during the Folding Process of a PDZ domain Nature Struct. Mol Biol. 17, 1431-1437.
