G. Marius Clore - Selected Publications#

Marius Clore is one of the most cited, important and influential scientists in the fields of biomolecular NMR, molecular biophysics and biophysical chemistry. Clore has authored over 500 peer-reviewed publications with an H-index of 140 and a citation count of >86,000 on Google Scholar. He is an original member of ISI's 2001 Highly Cited Researchers Database in the Biology & Biochemistry and Chemistry Sections (http://highlycited.com/isihighlycited.htm), and was listed in the top 35 in the H-index rankings of living chemists (http://www.rsc.org/images/H-index%20ranking%20of%20living%20chemists%28December%202011%29_tcm18-211414.pdf) published by the Royal Society of Chemistry.

J. Iwahara and G.M. Clore. (2006) Detecting transient intermediates in macromolecular binding by paramagnetic NMR. Nature 440, 1227-1230.

J. Iwahara, M. Zweckstetter and G.M. Clore (2006) NMR structural and kinetic characterization of a homeodomain diffusing and hopping on non-specific DNA. Proc. Natl. Acad. Sci. U.S.A. 103, 15062-15067.

C. Tang, J. Iwahara and G.M. Clore (2006) Visualization of transient encounter complexes in protein-protein association. Nature 444, 383-386

C. Tang, C. Schwieters and G.M. Clore (2007) Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR. Nature 449, 1078-1081.

C. Tang, J.M. Louis, A. Aniana, J.-Y. Suh, and G.M. Clore (2008) Visualizing transient events in N-terminal auto-processing of HIV-1 protease. Nature 455, 693-696.

G.M. Clore and J. Iwahara (2009) Theory, practice and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes. Chemical Reviews 109, 4108-4139

C.D. Schwieters, J.-Y. Suh, A. Grishaev, R. Ghirlando, Y. Takayama and G.M. Clore (2010) Solution structure of the 128 kDa enzyme I dimer from Escherichia coli and its 146 kDa complex with HPr using residual dipolar couplings and small- and wide-angle X-ray scattering. J. Am. Chem. Soc. 132, 13026-13045. (41 citations)

N.J. Anthis, M. Doucleff and G.M. Clore (2011) Transient, sparsely-populated compact states of apo and calcium-loaded calmodulin probed by paramagnetic relaxation enhancement: interplay of conformational selection and induced fit. J. Am. Chem. Soc. 133, 18966-18974

N.L. Fawzi, J. Ying, R. Ghirlando, D.A. Torchia and G.M. Clore (2011) Atomic resolution dynamics on the surface of amyloid β protofibrils probed by solution NMR. Nature 480, 268-272.

D.S. Libich, N.L. Fawzi, J. Ying and G.M. Clore (2013) Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR. Proc. Natl. Acad. Sci. U.S.A. 110, 11361-11366.

D.S. Libich, V. Tugarinov and G.M. Clore (2015) Intrinsic unfoldase/foldase activity of the chaperonin GroEL directly demonstrated using multinuclear relaxation-based NMR. Proc. Natl. Acad. Sci. U. S. A. 112, 8817-8823.

S.A. Kotler, V. Tugarinov, T. Schmidt, A. Ceccon, D.S. Libich, DR. Ghirlando, C.D. Schwieters and G.M. Clore (2019) Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR. Proc. Natl. Acad. Sci. U. S. A. 116, 3562-3571.

A. Ceccon, V. Tugarinov, R. Ghirlando, and G.M. Clore (2020) Abrogation of pre-nucleation, transient oligomerization of the Huntingtin exon-1 protein by human profilin-I. Proc. Natl. Acad. Sci. U.S.A. 117, 5844-5852.
A. Ceccon, V. Tugarinov, F. Torricella, and G.M. Clore (2022) Quantitative NMR analysis of the kinetics of prenucleation oligomerization and aggregation of pathogenic huntingtin exon-1 protein. Proc. Natl. Acad. Sci. U.S.A. 119, e2207690119.