Dimitrios Boumpas - Selected Publications#

1. Boumpas DT, Anastassiou ED, Older SA, Tsokos GC, Nelson DL, Balow JE. Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription. J Clin Invest 87: 1739-47, 1991.

2. Boumpas DT, Austin HA III, Vaughan EM, Klippel JH, Steinberg AD, Yarboro CH, Balow JE.: Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis. Lancet 340:741-5, 1992

3. Paliogianni F, Raptis A, Ahuja SS, Najjar SM, Boumpas DT: Negative transcriptional regulation of the human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT. J Clin Invest91:1481-9, 1993.

4. Paliogianni F, Kincaid RL, Boumpas DT: Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways. J Exp Med178:1813-7, 1993.

5. Hama N, Paliogianni F, Fessler BJ, Boumpas DT: Calcium/calmodulin dependent protein kinase II downregulates both calcineurin and protein kinase C mediated pathways for cytokine gene transcription in human T cells. J Exp Med181:1217-22, 1995.

6. Papadimitraki ED, Choulaki C, Koutala E ….Boumpas DT. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum. 2006 Nov;54(11):3601-11.

7. Bertsias GK, Nakou M, Choulaki C, …., Boumpas DT. Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus. Arthritis Rheum. 2009 Jan;60(1):207-18.

8. Nakou M, Knowlton N, Frank MB, ….Boumpas DT. Gene expression in systemic lupus erythematosus: bone marrow analysis differentiates active from inactive disease and reveals apoptosis and granulopoiesis signatures. Arthritis Rheum. 2008 Nov;58(11):3541-9 I

9. Stagakis E, Bertsias G, Verginis P…, Boumpas DT. Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression. Ann Rheum Dis. 2011 Aug;70(8):1496-506.

10.Papadaki E, Fanouriakis A, Kavroulakis E, Karageorgou D, Sidiropoulos P, Bertsias G, Simos P, Boumpas DT. Neuropsychiatric lupus or not? Cerebral hypoperfusion by perfusion-weighted MRI in normal-appearing white matter in primary neuropsychiatric lupus erythematosus. Ann Rheum Dis. 2018 Mar; 77(3):441-448