Alfred Wittinghofer - Curriculum Vitae#

  • born in Goch, Kreis Kleve, Germany, 23.5.1943
  • son of Josef and Else Wittinghofer
  • married to Uschi Wittinghofer, father of two sons, Pan and Henk
  • Easter 1963: Abitur at the Friedrich-Spee-Gymnasium Geldern
  • 1962-1968: Study of Chemistry at the Technische Hochschule Aachen, Germany
  • June 1968: Diploma
  • Diploma work and Doctoral thesis at the German Wool Research Institute in Aachen, subject: total chemical synthesis of insulin
  • March 1971: Ph.D
  • 1971-1973: postdoctoral fellow with Prof. R.G. Hiskey at the University of North Carolina, subject: modification of proteins
  • Since 1974 scientific assistant at the Max-Planck-Institut für medizinische Forschung, Heidelberg, Germany
  • Since 1980 head of an own research group: Studies on structure/function of EF-Tu, adenylate kinase, myosin heavy chain and the oncogene product Ras, biology of the Ras gene, interaction of Ras with regulators and effectors, studies on Ran regulated nuclear transport
  • 1992: Habilitation, University Heidelberg, Germany. Habilitation for Biochemistry at the Faculty of Medicine, University Heidelberg
  • 1993 – June 2009 Director of the Department ‘Structural Biology’ at the Max-Planck-Institute of Molecular Physiology, Dortmund, Germany General subject: GTP-binding proteins in cell biology
  • Honorarprofessor for Biochemistry at the Faculty of Chemistry Ruhr-University Bochum, Germany
  • Since July 2009 Emeritus Group at the Max-Planck-Institute of Molecular Physiology, Dortmund, Germany

  • Louis-Jeantet Prize for Medicine 2001
  • Richard-Kuhn-Medal of the Gesellschaft Deutscher Chemiker (GDCh), 2002
  • Deutscher Krebspreis 2003 der Deutschen Krebsgesellschaft e.V.
  • Otto-Warburg-Medal of the GBM, 2003

  • Nathan O. Kaplan Memorial Lecture, University of California, San Diego, 1997
  • Felix Hoppe-Seyler Lecturer 1998
  • Rudolf Virchow-Lecture, Medizinische Fakultät der Universität Würzburg, 2002
  • Otto-Warburg-Chemie Lecture, Otto-Warburg-Chemie-Foundation, University Bayreuth, 2004
  • Keynote lecture FASEB Summer Research Conference: Regulation and Function small GTPases, Saxton River 2008
  • Director Lecture, Sloan Kettering Comprehensive Cancer Center New York, 2008
  • NIH Director’s Lecture, U.S. Department of Health and Human Services, 2009
  • Keynote lecture: Conference Jacques-Monod, Regulation and Function of small GTPaases, Aussois 2009
  • Keynote Lecture Eurotox 2009, Dresden

  • EMBO Member
  • Member of the Academia Europaea
  • Senator Section Biochemistry/Biophysik of the Deutsche Akademie der Naturforscher Leopoldina
  • Member of the Nordrhein-Westfälische Akademie der Wissenschaften, Class for Naturwissenschaften und Medizin
  • Honorary Member of the Japanese Biochemical Society
  • Fellow of the European Academy of Cancer Sciences, since 2009

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