Beáta G. Vértessy - Selected Publications#

1: Pálinkás HL, Békési A, Róna G, Pongor L, Papp G, Tihanyi G, Holub E, Póti Á, Gemma C, Ali S, Morten MJ, Rothenberg E, Pagano M, Szűts D, Győrffy B, Vértessy BG.
Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments.
eLife. 2020 Sep; 9: e60498
https://elifesciences.org/articles/60498

2: Nyíri K, Mertens HDT, Tihanyi B, Nagy GN, Kőhegyi B, Matejka J, Harris MJ, Szabó JE, Papp-Kádár V, Németh-Pongrácz V, Ozohanics O, Vékey K, Svergun DI, Borysik AJ, Vértessy BG.
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.
Sci Rep. 2018 Mar 12;8(1):4326.
https://www.nature.com/articles/s41598-018-22145-8

3: Nagy GN, Suardíaz R, Lopata A, Ozohanics O, Vékey K, Brooks BR, Leveles I, Tóth J, Vértessy BG*, Rosta E.*
(*corresponding authors)
Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.
J Am Chem Soc. 2016;138(45):15035-15045.
https://pubs.acs.org/doi/10.1021/jacs.6b09012

4: Róna G, Scheer I, Nagy K, Pálinkás HL, Tihanyi G, Borsos M, Békési A, Vértessy BG.
Detection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications.
Nucleic Acids Res. 2016;44(3):e28.
https://academic.oup.com/nar/article/44/3/e28/2503069

5: Nagy GN, Marton L, Contet A, Ozohanics O, Ardelean LM, Révész A, Vékey K, Irimie FD, Vial H, Cerdan R, Vértessy BG.
Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates.
Angew Chem Int Ed Engl. 2014;53(49):13471-6.
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201408246

6: Szabó JE, Németh V, Papp-Kádár V, Nyíri K, Leveles I, Bendes AÁ, Zagyva I, Róna G, Pálinkás HL, Besztercei B, Ozohanics O, Vékey K, Liliom K, Tóth J, Vértessy BG.
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control.
Nucleic Acids Res. 2014;42(19):11912-20.
https://academic.oup.com/nar/article/42/19/11912/2902985

7: Róna G, Marfori M, Borsos M, Scheer I, Takács E, Tóth J, Babos F, Magyar A, Erdei A, Bozóky Z, Buday L, Kobe B, Vértessy BG.
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr D Biol Crystallogr. 2013;69(Pt 12):2495-505.
https://onlinelibrary.wiley.com/doi/abs/10.1107/S0907444913023354

8: Barabás O, Németh V, Bodor A, Perczel A, Rosta E, Kele Z, Zagyva I, Szabadka Z, Grolmusz VI, Wilmanns M, Vértessy BG.
Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.
Nucleic Acids Res. 2013;41(22):10542-55.
https://academic.oup.com/nar/article/41/22/10542/24354619

9: Muha V, Horváth A, Békési A, Pukáncsik M, Hodoscsek B, Merényi G, Róna G, Batki J, Kiss I, Jankovics F, Vilmos P, Erdélyi M, Vértessy BG.
Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement.
PLoS Genet. 2012;8(6):e1002738.
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002738

10: Horváth A, Vértessy BG.
A one-step method for quantitative determination of uracil in DNA by real-time PCR.
Nucleic Acids Res. 2010 Nov;38(21):e196.
https://academic.oup.com/nar/article/38/21/e196/2411894