Vladimir P. Skulachev - Selected publications#

• Dibrova D.V., Cherepanov D.A., Galperin M.Y., Skulachev V.P., Mulkidjanian A.Y. (2013) Evolution of cytochrome bc complexes: From membrane-anchored dehydrogenases of ancient bacteria to triggers of apoptosis in vertebrates. Biochim. Biophys. Acta-Bioenerg., 1827 (11): 1407-1427.

• Pustovidko A.V., Rokitskaya T.I., Severina I.I., Simonyan R.A., Trendeleva T.A., Lyamzaev K.G., Antonenko Y.N., Rogov A.G., Zvyagilskaya R.A., Skulachev V.P., Chernyak B.V. (2013) Derivatives of the cationic plant alkaloids berberine and palmatine amplify protonophorous activity of fatty acids in model membranes and mitochondria. Mitochondrion, 13 (5): 520-525.

• Trendeleva T.A., Sukhanova E.I., Rogov A.G., Zvyagilskaya R.A., Seveina I.I., Ilyasova T.M., Cherepanov D.A., Skulachev V.P. (2013) Role of charge screening and delocalization for lipophilic cation permeability of model and mitochondrial membranes. Mitochondrion, 13 (5): 500-506.

• Severin F.F., Feniouk B.A., Skulachev V.P. (2013) Advanced glycation of cellular proteins as a possible basic component of the "master biological clock". Biochem.-Moscow, 78 (9): 1043-1047.

• Plotnikov E.Y., Morosanova M.A., Pevzner I.B., Zorova L.D., Manskikh V.N., Pulkova N.V., Galkina S.I., Skulachev V.P., Zorov D.B. (2013) Protective effect of mitochondria-targeted antioxidants in an acute bacterial infection. Proc. Natl. Acad. Sci. U. S. A., 110 (33): 0-0.

• Tsarev D.A., Zverev R.S., Kazmina E.M., Tashlitsky V.N., Skulachev V.P. (2013) Evaluating the Stability of a Cationic Plastoquinone Derivative (PDTP) in Visomitin Eye Drops. Pharm. Chem. J., 47 (4): 219-224.

• Severina I.I., Severin F.F., Korshunova G.A., Sumbatyan N.V., Ilyasova T.M., Simonyan R.A., Rogov A.G., Trendeleva T.A., Zvyagilskaya R.A., Dugina V.B., Domnina L.V., Fetisova E.K., Lyamzaev K.G., Vyssokikh M.Y., Chernyak B.V., Skulachev M.V., Skulachev V.P., Sadovnichii V.A. (2013) In search of novel highly active mitochondria-targeted antioxidants: Thymoquinone and its cationic derivatives. FEBS Lett., 587 (13): 2018-2024.

• Rokitskaya T.I., Ilyasova T.M., Severina I.I., Antonenko Y.N., Skulachev V.P. (2013) Electrogenic proton transport across lipid bilayer membranes mediated by cationic derivatives of rhodamine 19: comparison with anionic protonophores. Eur. Biophys. J. Biophys. Lett., 42 (6): 477-485.

• Kirpatovsky V.I., Plotnikov E.Y., Mudraya I.S., Golovanov S.A., Drozhzheva V.V., Khromov R.A., Chernikov D.Y., Skulachev V.P., Zorov D.B. (2013) Role of oxidative stress and mitochondria in onset of urinary bladder dysfunction under acute urine retention. Biochem.-Moscow, 78 (5): 542-548.

• Antonenko Y.N., Khailova L.S., Knorre D.A., Markova O.V., Rokitskaya T.I., Ilyasova T.M., Severina I.I., Kotova E.A., Karavaeva Y.E., Prikhodko A.S., Severin F.F., Skulachev V.P. (2013) Penetrating Cations Enhance Uncoupling Activity of Anionic Protonophores in Mitochondria. PLoS One, 8 (4):

• Silachev D.N., Isaev N.K., Pevzner I.B., Zorova L.D., Stelmashook E.V., Novikova S.V., Plotnikov E.Y., Skulachev V.P., Zorov D.B. (2012) The Mitochondria-Targeted Antioxidants and Remote Kidney Preconditioning Ameliorate Brain Damage through Kidney-to-Brain Cross-Talk. PLoS One, 7 (12):

• Lokhmatikov A.V., Voskoboynikova N., Cherepanov D.A., Steinhoff H.J., Skulachev V.P., Mulkidjanian A.Y. (2012) Oxidation of cardiolipin in liposomes: A new insight into the primary steps of mitochondria-triggered apoptosis. Biochim. Biophys. Acta-Bioenerg., 1817: 0-0.

• Isaev N.K., Novikova S.V., Stelmashook E.V., Barskov I.V., Silachev D.N., Khaspekov L.G., Skulachev V.P., Zorov D.B. (2012) Mitochondria-targeted plastoquinone antioxidant SkQR1 decreases trauma-induced neurological deficit in rat. Biochem.-Moscow, 77 (9): 996-999.

• Plotnikov E.Y., Silachev D.N., Jankauskas S.S., Rokitskaya T.I., Chupyrkina A.A., Pevzner I.B., Zorova L.D., Isaev N.K., Antonenko Y.N., Skulachev V.P., Zorov D.B. (2012) Mild uncoupling of respiration and phosphorylation as a mechanism providing nephro- and neuroprotective effects of penetrating cations of the SkQ family. Biochem.-Moscow, 77 (9): 1029-1037.

• Il'yasova T.M., Rokitskaya T.I., Severina I.I., Antonenko Y.N., Skulachev V.P. (2012) Substitution of ether linkage for ester bond in phospholipids increases permeability of bilayer lipid membrane for SkQ1-type penetrating cations. Biochem.-Moscow, 77 (9): 1038-1043.

• Antonenko Y.N., Perevoshchikova I.V., Rokitskaya T.I., Simonyan R.A., Tashlitsky V.V., Skulachev V.P. (2012) Effect of liposomes on energy-dependent uptake of the antioxidant SkQR1 by isolated mitochondria. J. Bioenerg. Biomembr., 44 (4): 453-460.

• Skulachev V.P. (2012) What is "phenoptosis" and how to fight it?. Biochem.-Moscow, 77 (7): 689-706.

• Gavrilova N.S., Gavrilov L.A., Severin F.F., Skulachev V.P. (2012) Testing predictions of the programmed and stochastic theories of aging: Comparison of variation in age at death, menopause, and sexual maturation. Biochem.-Moscow, 77 (7): 754-760.

• Jankauskas S.S., Plotnikov E.Y., Morosanova M.A., Pevzner I.B., Zorova L.D., Skulachev V.P., Zorov D.B. (2012) Mitochondria-targeted antioxidant SkQR1 ameliorates gentamycin-induced renal failure and hearing loss. Biochem.-Moscow, 77 (6): 666-670.

• Lyamzaev K.G., Pustovidko A.V., Simonyan R.A., Rokitskaya T.I., Domnina L.V., Ivanova O.Y., Severina I.I., Sumbatyan N.V., Korshunova G.A., Tashlitsky V.N., Roginsky V.A., Antonenko Y.N., Skulachev M.V., Chernyak B.V., Skulachev V.P. (2011) Novel Mitochondria-Targeted Antioxidants: Plastoquinone Conjugated with Cationic Plant Alkaloids Berberine and Palmatine. Pharmaceutical Research, 28 (11): 2883-2895.

• Pevzner I.B., Plotnikov E.Y., Chupyrkina A.A., Jankauskas S.S., Silachev D.N., Skulachev V.P., Zorov D.B. (2011) Mechanisms of nephroprotective effect of mitochondria-targeted antioxidants under rhabdomyolysis and ischemia/reperfusion. FEBS Journal, 278: 400.

• Silachev D.N., Pevzner I.B., Zorova L.D., Plotnikov E.Y., Gulyaev V.V., Pirogov Y.A., Isaev N.K., Skulachev V.P., Zorov D.B. (2011) New generation of permeated cations as potential agents to rescue from ischemic stroke. FEBS Journal, 278: 280.

• Skulachev M.V., Antonenko Y.N., Anisimov V.N., Chernyak B.V., Cherepanov D.A., Chistyakov V.A., Egorov M.V., Kolosova N.G., Korshunova G.A., Lyamzaev K.G., Plotnikov E.Y., Roginsky V.A., Savchenko A.Y., Severina I.I., Severin F.F., Shkurat T.P., Tashlitsky V.N., Shidlovsky K.M., Vyssokikh M.Y., Zamyatnin A.A., Zorov D.B., Skulachev V.P. (2011) Mitochondrial-Targeted Plastoquinone Derivatives. Effect on Senescence and Acute Age-Related Pathologies. Current Drug Targets, 12 (6): 800-826.

• Skulachev V.P. (2011) Mitochondria-targeted penetrating ions as inhibitors of the aging program and obesity. FEBS Journal, 278: 39.

• Antonenko Y.N., Avetisyan A.V., Cherepanov D.A., Knorre D.A., Korshunova G.A., Markova O.V., Ojovan S.M., Perevoshchikova I.V., Pustovidko A.V., Rokitskaya T.I., Severina I.I., Simonyan R.A., Smirnova E.A., Sobko A.A., Sumbatyan N.V., Severin F.F., Skulachev V.P. (2011) Derivatives of Rhodamine 19 as Mild Mitochondria-targeted Cationic Uncouplers. Journal of Biological Chemistry, 286 (20): 17831-17840.

• Plotnikov E.Y., Chupyrkina A.A., Jankauskas S.S., Pevzner I.B., Silachev D.N., Skulachev V.P., Zorov D.B. (2011) Mechanisms of nephroprotective effect of mitochondria-targeted antioxidants under rhabdomyolysis and ischemia/reperfusion. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1812 (1): 77-86.

• Skulachev V.P. (2010) Discovery of a Photosynthesizing Animal that Can Survive for Months in a Light-Dependent Manner. Biochemistry-Moscow, 75 (12): 1498-1499.

• Popova E.N., Pletjushkina O.Y., Dugina V.B., Domnina L.V., Ivanova O.Y., Izyumov D.S., Skulachev V.P., Chernyak B.V. (2010) Scavenging of Reactive Oxygen Species in Mitochondria Induces Myofibroblast Differentiation. Redox Signaling, 13 (9): 1297-1307.

• Rokitskaya T.I., Sumbatyan N.V., Tashlitsky V.N., Korshunova G.A., Antonenko Y.N., Skulachev V.P. (2010) Mitochondria-targeted penetrating cations as carriers of hydrophobic anions through lipid membranes. Biochimica et Biophysica Acta-Biomembranes, 1798 (9): 1698-1706.

• Danshina M.I., Silachev D.N., Pevzner I.B., Plotnikov E.Y., Pirogov Y.B., Isaev N.K., Skulachev V.P., Zorov D.B. (2010) Evaluation of neuroprotective abilities of the novel mitochondria-targeted antioxidants. Biochimica et Biophysica Acta-Bioenergetics, 1797: 82.