Ton Schumacher - Selected Publications#

1. Stronen, E., Toebes, M., Kelderman, S., van Buuren, M.M., Yang, W., van Rooij, N., Donia, M., Boschen, M.L., Lund-Johansen, F., Olweus, J. & Schumacher, T.N. Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science (2016) 352, 1337-1341.

2. Schumacher, T.N. & Schreiber, R.D. Neoantigens in cancer immunotherapy (review). Science (2015) 348, 69-74.

3. Linnemann, C., van Buuren, M.M., Bies, L., Verdegaal, E.M., Schotte, R., Calis, J.J., Behjati, S., Velds, A., Hilkmann, H., Atmioui, D.E., Visser, M., Stratton, M.R., Haanen, J.B., Spits, H., van der Burg, S.H. & Schumacher, T.N. High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma. Nat Med (2015) 21, 81-85.

4. Ariotti, S., Hogenbirk, M.A., Dijkgraaf, F.E., Visser, L.L., Hoekstra, M.E., Song, J.Y., Jacobs, H., Haanen, J.B. & Schumacher, T.N. T cell memory. Skin-resident memory CD8(+) T cells trigger a state of tissue-wide pathogen alert. Science (2014) 346, 101-105.

5. van Rooij, N., van Buuren, M.M., Philips, D., Velds, A., Toebes, M., Heemskerk, B., van Dijk, L.J., Behjati, S., Hilkmann, H., El Atmioui, D., Nieuwland, M., Stratton, M.R., Kerkhoven, R.M., Kesmir, C., Haanen, J.B., Kvistborg, P. & Schumacher, T.N. Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. J Clin Oncol (2013) 31, e439-442.

6. Gerlach, C., Rohr, J.C., Perie, L., van Rooij, N., van Heijst, J.W., Velds, A., Urbanus, J., Naik, S.H., Jacobs, H., Beltman, J.B., de Boer, R.J. & Schumacher, T.N. Heterogeneous differentiation patterns of individual CD8+ T cells. Science (2013) 340, 635-639.

7. Naik, S.H., Perie, L., Swart, E., Gerlach, C., van Rooij, N., de Boer, R.J. & Schumacher, T.N. Diverse and heritable lineage imprinting of early haematopoietic progenitors. Nature (2013) 496, 229-232.

8. Bendle, G.M., Linnemann, C., Hooijkaas, A.I., Bies, L., de Witte, M.A., Jorritsma, A., Kaiser, A.D., Pouw, N., Debets, R., Kieback, E., Uckert, W., Song, J.Y., Haanen, J.B. & Schumacher, T.N. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med (2010) 16, 565-570.

9. Hadrup, S.R., Bakker, A.H., Shu, C.J., Andersen, R.S., van Veluw, J., Hombrink, P., Castermans, E., Thor Straten, P., Blank, C., Haanen, J.B., Heemskerk, M.H. & Schumacher, T.N. Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers. Nat Methods (2009) 6, 520-526.

10. Toebes, M., Coccoris, M., Bins, A., Rodenko, B., Gomez, R., Nieuwkoop, N.J., van de Kasteele, W., Rimmelzwaan, G.F., Haanen, J.B., Ovaa, H. & Schumacher, T.N. Design and use of conditional MHC class I ligands. Nat Med (2006) 12, 246-251.