Mark Sansom - Publications#

In total, nearly 600 publications, with an overall h-index = 86 (Web of Science).

10 of recent major publications from the past 5 years:

1. Song, W., Duncan, A.L. & Sansom, M.S.P. (2021) Modulation of adenosine A2a receptor oligomerisation by receptor activation and PIP2 interactions. Structure 29: 1312-1325.e3.

2. Lynch, C.I., Rao, S., & Sansom, M.S.P. (2020) Water in nanopores and biological channels: a molecular simulation perspective. Chem. Rev. 120: 10298–10335.

3. Klesse, G., Rao, S., Tucker, S.J. & Sansom, M.S.P. (2020) Induced polarization in molecular dynamics simulations of the 5-HT3 receptor channel. J. Amer. Chem. Soc. 142: 9415-9427.

4. Duncan, A.L., Corey, R.A. & Sansom, M.S.P. (2020) Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels. Proc. Natl. Acad. Sci. USA 117: 7803-7813.

5. Yamamoto, E., Domański, J., Naughton, F.B., Best, R.B., Kalli, A.C., Stansfeld, P.J., & Sansom, M.S.P. (2020) Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes. Science Advances 6: eaay5736.

6. Duncan, A., Song, W. & Sansom, M.S.P. (2020) Lipid-dependent regulation of ion channels and GPCRs: insights from structures and simulations. Ann. Rev. Pharmacol. Toxicol. 60:31-50.

7. Rao, S., Klesse, G., Stansfeld, P.J., Tucker, S.J., & Sansom, M.S.P. (2019) A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates. Proc. Natl. Acad. Sci. USA 116: 13989-13995.

8. Song, W., Yen, H.-Y., Robinson, C.V., & Sansom, M.S.P. (2019) State-dependent lipid interactions with the A2a receptor revealed by MD simulations using in vivo-mimetic membranes. Structure 27: 392–403.

9. Chavent, M., Duncan, A., Rassam, P., Birkholz, O., Hélie, J., Reddy, T., Beliaev, D., Hambly, B., Piehler, J., Kleanthous, C. & Sansom, M.S.P. (2018) How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membranes Nature Comms. 9: 2846.

10. Yen, H.-Y., Hoi, K.K., Liko, I., Hedger, G., Horrell, M.R., Song. W., Wu, D., Heine, P., Warne, T., Lee, Y., Carpenter, B., Plückthun, A., Tate, C.G., Sansom, M.S.P. & Robinson, C.V. (2018) PtdIns(4,5)P2 stabilises active states of GPCRs and enhances selectivity of G-protein coupling. Nature 559: 423–427.