Maria G. Roncarolo - Selected publications#

• A. Valle, T. Jofra, A. Stabilini, M. Atkinson, M.G. Roncarolo and M. Battaglia. (2009). Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice. Diabetes. 58: 875-881.
• M. Battaglia and M.G. Roncarolo. (2009). The fate of human Treg cells. Immunity 30: 763-765.
• G. Serafini, M. Andreani, M. Testi, M. Battarra, A. Bontadini, K. Fleischhauer, S. Marktel, G. Lucarelli, M.G. Roncarolo, and R. Bacchetta. (2009). Type 1 regulatory T cells are associated with persistent split erythroid/lymphoid chimerism after allogeneic hematopoietic stem cell transplantation for thalassemia. Haematologica. 94: 1415-1426.
• A.Annoni, B.D. Brown, A. Cantore, L. Sergi Sergi, L. Naldini and M.G. Roncarolo. (2009). In vivo delivery of a microRNA regulated transgene induces antigen-specific regulatory T cells and promotes immulogical tolerance. Blood. 114: 5152-5161.
• S. Di Nunzio, M. Cecconi, L. Passerini, A.N. McMurchy, U. Baron, I. Turbachova, S. Vignola, S. Valencic, A. Tommasini, A. Junker, G. Cazzola, S. Olek , M.K. Levings, L. Perroni, M.G. Roncarolo, and R. Bacchetta. (2009). Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations. Blood 114: 4138-4141.
• N. Gagliani, A. Ferraro, M.G. Roncarolo, and M. Battaglia. (2009). Autoimmune diabetic patients undergoing allogeneic islet transplantation: are we ready for a regulatory T-cell therapy? Immunol Lett 127: 1-7.
• N. Gagliani, T. Jofra, A. Stabilini, A. Valle, M. Atkinson, M.G. Roncarolo, and M. Battaglia. (2010). Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplantation. Diabetes 59:433-439.
• V. Pacciani, S. Gregori, L. Chini, S. Corrente, M. Chianca, V. Moschese, P. Rossi, M.G. Roncarolo, and F. Angelini. (2010). Induction of adergi allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites. J Allergy Clin Immunol. 125:727-736.
• S. Gregori, D. Tomasoni,, V. Pacciani, M. Scirpoli, M. Battaglia, C.F. Magnani, E. Hauben, and M.G.Roncarolo. (2010). Differentiation of type 1 T regulatory (Tr1) cells by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway. Blood.116: 935-944.
• C. Cancrini, F. Ferrua, A. Scarselli, I. Brigida, M.L. Romiti, G. Barera, A. Finocchi, M.G. Roncarolo, M. Caniglia, and A. Aiuti. (2010). Role of reduced intensity conditioning in T-cell and B-cell immune reconstitution after HLA-identical bone marrow transplantation in ADA-SCID. Haematologica. 95: 1778-1782.
• R.Bacchetta, S. Gregori, G. Serafini, C. Sartirana, U.Schultz, E.Zino, S. Tomiuk, U.Jan"en, M. Ponzoni C.T. Paties, K.Fleischhauer, and M.G. Roncarolo (2010). Molecular and functional characterization of alloantigen-specific anergic T-cells suitable for cell therapy. Haematologica. 95: 2134-2143.
• S. Gregori, M.G. Roncarolo, and R. Bacchetta (2010). Methods for in vitro generation of human type 1 regulatory T cells. Methods Mol Biol. 677:31-46.
• M. Rossetti, S. Gregori, and M.G. Roncarolo (2010). Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells. Eur J Immunol. 40: 3097-3106.
• S. Huber, N. Gagliani, E. Esplugues, W. O"Connor Jr., F.J. Huber, A. Chaudhry, M. Kamanaka, Y. Kobayashi, C.J. Booth, A.Y. Rudensky, M. Battaglia, M.G. Roncarolo, and R.A. Flavell. (2011). Th17 cells express IL-10Ra and are controlled by Foxp3- and Foxp3+ regulatory CD4+ T cells in an IL-10 dependent manner. Immunity 34: 554-565.
• C.F. Magnani, G. Alberigo, R. Bacchetta, G. Serafini, M. Andreani, M.G. Roncarolo, and S. Gregori. (2011). Killing of myeloid APC via HLA Class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells. Eur J Immunol.
• J. Mátrai, A. Cantore, C.C. Bartholomae, A. Annoni, W.Wang, A. Acosta-Sanchez, E. Samara-Kuko, L. De Waele, L. Ma, P. Genovese, M. Damo, A. Arens, K. Goudy, T.C. Nichols, C.von Kalle, M.K. L Chuah, M.G. Roncarolo, M. Schmidt, T. Vandendriessche, and Naldini L. (2011). Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. Hepatology, 53:1696-1707.
• L. Passerini, S. Di Nunzio, S. Gregori, E. Gambineri, M. Cecconi, M.G. Seidel, G. Cazzola, L. Perroni, A. Tommasini, S. Vignola, L. Guidi, M.G. Roncarolo, and R. Bacchetta. (2011). Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome. Eur J Immunol. 41:1120-1131.
• M.G Roncarolo, S. Gregori, B. Lucarelli, F. Ciceri, R. Bacchetta (2011). Clinical tolerance in allogeneic hematopoietic stem cell transplantation. Immunological Reviews, 241:145-163.
• E. Tresoldi, I. Dell'albani, A. Stabilini, T. Jofra, A. Valle, N. Gagliani, A. Bondanza, M.G. Roncarolo, and M. Battaglia. (2011). Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells. Haematologica. Prepublished online May 12, 2011.