Cesare Montecucco - Selected publications#

• Tonello, F., Ascenzi, P. & Montecucco, C. The Metalloproteolytic Activity Of The Anthrax Lethal Factor Is Substrate-Inhibited. J. Biol. Chem. (2003), 278, In Press

• Caccin, P., Rossetto, O., Rigoni, M., Schiavo, G. & Montecucco, C.. Vamp/Synaptobrevin Cleavage By Tetanus And Botulinum Neurotoxins Is Strongly Enhanced By Acidic Liposomes. FEBS Lett. (2003) In Press.

• Nishioka, H., Baesso I., Semenzato, G., Trentin L., Rappuoli, R., Del Giudice, G. & Montecucco C. The Neutrophil Activating Protein Of Helicobacter Pylori (Hp-Nap) Activates The Mapk Pathway In Human Neutrophils. Eur. J. Immunol. (2003) 33, 840-849.

• Montecucco, C. & De Bernard, M. Molecular And Cellular Mechanisms Of Action Of The Vacuolating Cytotoxin (Vaca) And Neutrophil-Activating Protein (Hp-Nap) Virulence Factors Of Helicobacter Pylori. Microbes And Infection (2003) 5, 715 - 721.

• Neco P., Rossetto, O., Gil A., Montecucco, C. & Gutierrez, L. Taipoxin Induces F-Actin Fragmentation And Enhances Release Of Catecholamines In Bovine Chromaffin Cells. J. Neurochem. (2003) 85 329-337.

• Luvisetto, S., Rossetto, O., Montecucco, C. & Pavone, F. Toxicity Of Botulinum Neurotoxins In Central Nervous System Of Mice. Toxicon (2003) 41, 475-481.

• Scapini, P., Nardelli, B., Nadali, G., Calzetti, F., Pizzolo, G., Montecucco, C. & Cassatella, M. G-Csf-Stimulated Neutrophils Are A Prominent Source Of Functional Blys. J. Exp. Med. , (2003) 197, 840-849.

• Tugnoli, V., Marchese Ragona, R., Eleopra, R., Quatrale, R., Capone, J. G., Pastore, A., Montecucco, C. & De Grandis, E. The Role Of Gustatory Flushing In Frey's Sindrome And Its Treatment With Botulinum Toxin Type A. Clin Auton Res 12 (2002) 3, 174-178

• Zanotti, G., Papinutto, E., Dundon, W.G., Battistutta, R., Seveso, M., Del Giudice, G. Rappuoli, R., & Montecucco, C. Structure Of The Neutrophil-Activating Protein From Helicobacter Pylori. J. Mol. Biol. (2002) 323, 125-130.

• Seydel, A., Tasca, E., Berti, D., Rappuoli, R., Del Giudice, G. & Montecucco, C. Characterization And Immunogenicity Of The Cagf Protein Of The Cag Pathogenicity Island Of Helicobacter Pylori. Infect. Immun. (2002) 70, 6468-6470.

• Tonello, F., Seveso, M., Marin, O., Mock, M. & Montecucco, C. Pharmacology: Screening Inhibitors Of Anthrax Lethal Factor. Nature (2002) 418, 386.

• Moschioni, M., Tombola, F., De Bernard, M., Coehlo, A., Zitzer, A., Zoratti, M. & Montecucco, C. The Vibrio Cholerae Hemolysin Anion Channel Is Required For Cell Vacuolation And Death. Cell. Microbiol. (2002) 4, 397-409.

• Eleopra, R., Tugnoli, V., Quatrale, R., Gastaldo, E., Rossetto, O., De Grandis, D. & Montecucco, C. Botulinum Neurotoxins Serotype A And C Do Not Affect Motor Units Survival In Humans: An Electrophysiological Study By Motor Unit Counting. Clin. Neurophysiol. (2002) 113, 1258-64.

• Papinutto, E., Dundon, W. G., Pitulis, N., Battistutta, R., Montecucco, C. & Zanotti, G. Structure Of Two Iron-Binding Proteins From Bacillus Anthracis . J. Biol. Chem. (2002) 277, 15093-15098.

• Montemurro, P., Nishioka, H., De Bernard, M., Del Giudice, G., Rappuoli, R. & Montecucco, C. The Neutrophil Activating Protein (Hp-Nap) Of Helicobacter Pylori Is A Potent Stimulant Of Mast Cells. Eur. J. Immunol. (2002) 32, 671-676.

• De Bernard, M., Moschioni, M., Habermann, A., Griffiths, G. & - Montecucco, C. Cell Vacuolization Induced By Helicobacter Pylori Vaca Cytotoxin Does Not Depend On Late Endosomal Snares. Cell. Microbiol., (2002) 4, 11-18.

• Rossetto, O., Caccin, P., Seveso, M. & Montecucco, C. Botulinum Neurotoxins Are Metalloproteases Specific For Snare Proteins. Curr. Probl. Dermatol. (2002) 30, 117-125.

• Ascenzi P., Visca P., Ippolito G., Spallarossa A., Bolognesi M. & Montecucco C. Anthrax Toxin: A Tripartite Lethal Combination. FEBS Lett. (2002) 531, 384-388.

• Dundon, W.G., Nishioka, H., Polenghi, A., Papinutto, E., Zanotti, G., Montemurro, P., Del Giudice, G., Rappuoli, R. & Montecucco, C. The Neutrophil-Activating Protein Of Helicobacter Pylori. Int. J. Med. Microbiol. (2002) 291, 545-550.

• De Bernard, M. & Montecucco, C. (2003). Microbial Subversion Of Host Cells. Pp.177-198. Cambridge University Press, Cambridge, Uk.

• Montecucco, C. Neurotoxins. Wiley Encyclopedia Of Molecular Medicine, Vol. 5, 2260-2261 (2002).

• Montecucco, C. Diphtheria Toxin. Wiley Encyclopedia Of Molecular Medicine, Vol. 5, 1057-1058 (2002).

• Rossetto O., Tonello F. And Montecucco C. (2002). Proteases. In: Bacterial Protein Toxins (Eds. Barbieri J., Rappuoli R., Iglewski B. And Burns D.). American Society For Microbiology Press. Pp.271-282.

• Rossetto O., Caccin P., Rigoni M., Seveso M., Tonello F., Stevens R.C. And Montecucco C. (2002). The Metalloprotease Activity Of Tetanus And Botulinum Neurotoxins. In: Scientific And Therapeutic Aspect Of Botulinum Toxin" (Eds Jankovic J., Hallett M. And Brin M.F.). Pp. 3-10. Lippincott Williams And Wilkins, Philadelphia.