Fatima Mechta-Grigoriou - Selected publications#

1- Batista L, Gruosso T, Mechta-Grigoriou F. Ovarian cancer emerging subtypes: Role of oxidative stress and fibrosis in tumour development and response to treatment.
Int J Biochem Cell Biol. 2013 Jun;45(6):1092-8. (5-year IF, 4.8)

2- Mateescu B., Batista L., Cardon M., Gruosso T., de Feraudy Y., Mariani O., Nicolas A., Meyniel JP., Cottu P., Sastre-Garau X. and Mechta-Grigoriou F. miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response.
Nature Medicine, 2011, Nov 20;17(12):1627-35 (5-year IF, 26.4)

3- Cook T. H, Tarzi R, D'Souza Z, Laurent G, Lin WC, Aitman TJ, Mechta-Grigoriou F, Behmoaras J. AP-1 Transcription Factor JunD Confers Protection from Accelerated Nephrotoxic Nephritis and Control Podocyte-Specific Vegfa Expression.
American Journal of Pathology. 2011, Jul;179(1):134-40. (5-year IF, 5.6)

4- Toullec A, Gerald D, Despouy G, Bourachot B, Cardon M, Lefort S, Richardson M, Rigaill G, Parrini MC, Lucchesi C, Bellanger D, Stern MH, Dubois T, Sastre-Garau X, Delattre O, Vincent-Salomon A, Mechta-Grigoriou F. Oxidative stress promotes myofibroblast differentiation and tumour spreading.
EMBO Molecular Medicine, 2010, 2(6):211-30 (5-year IF, 10.3)

5- Laurent G., Solari F., Mateescu B., Karaca M., Castel J., Bourachot B., Magnan C., Billaud M. and Mechta-Grigoriou F. Oxidative stress contributes to aging by inducing pancreatic angiogenesis and insulin-signaling.
Cell Metabolism, 2008, 7(2): 113-124 (5-year IF, 17.7)

6- Caffarel MM., Moreno-Bieno G., Cerruti C., Palacios J. Guzman M., Mechta-Grigoriou F., and Sanchez C. Role of JunD in the anti-proliferative effect of tetrahydrocannabinol on human breast cancer cells.
Oncogene, 2008, 27(37):5033-44 (5-year IF, 6.9)

7- Pouysségur, J. and Mechta-Grigoriou, F. Redox regulation of the Hypoxia Inducible Factor.
Biol. Chem. 2006, 387, 1337-1346. (5-year IF, 2.9)

8- Gerald, D., Berra, E., Frappart, Y.M, Chan, D., Giaccia, A.J., Mansuy, D., Pouysségur, J., Yaniv, M., and Mechta-Grigoriou, F. JunD reduces tumor angiogenesis by protecting cells from oxidative stress.
Cell, 2004,118, 781-794 (5-year IF, 34.7)

9- Patent:
“Dual gene expression signature to predict clinical outcome and therapeutic response of patients with ovarian cancer.” European patent deposit, Extension in USA (Reference number EP11306512.2)