Susanne Mandrup - Publications#

Full list of publications 2014


Selected publications

1. R. Nielsen*, T. Å. Pedersen*, D. Hagenbeek*, P. Moulos, R. Siersbæk, E. Megens, M. Børgesen, K.-J. Francoijs, S. Mandrup¤ and H. G. Stunnenberg¤ (2008) Genome-wide profiling of PPARγ:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes & Dev. 22, 2953 - 2967. (* equal contribution, ¤ co-correspondence)(DOI:10.1101/gad.501108, Cites = 200)

2. R. Siersbæk, R. Nielsen, S. John, M.-H. Sung, S. Baek, A. Loft, G. L. Hager¤, S. Mandrup¤ (2011) Extensive chromatin remodeling and establishment of transcription factor ‘hotspots’ during early adipogenesis. EMBO J 30, 1459-72 (highlighted in ‘Have You Seen’ in the same issue (¤ co-correspondence)(DOI:10.1038/emboj.2011.65, Cites = 54)

3. R. Siersbæk, R. Nielsen, S. Mandrup (2012) Transcriptional networks and chromatin remodeling controlling adipogenesis. Trends Endocrinol. Metab. 23, 56-64. (Featured article and front cover, rated in top 10 articles in 2012 by the Editorial Board) (DOI:10.1016/j.tem.2011.10.001, Cites = 13)

4. M. Børgesen, T. Å. Pedersen, S. vanHeeringen, B. Gross, Hagenbeek, C. Bindesbøll, S. Caron, F. Lalloyer, K. Steffensen, H. Nebb, J.-Å. Gustafsson, H. Stunnenberg, B. Staels, S. Mandrup (2012) Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals extensive sharing of binding sites. Mol. Cell. Biol. 32, 852-867 (DOI:10.1128/MCB.06175-11, Cites = 28)

5. M.S. Siersbæk*, A. Loft*, M. M. Aagaard*, R. Nielsen, S. F. Schmidt, N. Petrovic, J. Nedergaard, S. Mandrup (2012) Genome-wide profiling of PPARγ in primary epididymal, inguinal and brown adipocytes reveals depot-selective binding correlated with gene expression. Mol. Cell Biol. 32, 3452–3463. (Selected for spotlight in the issue)(DOI:10.1128/MCB.00526-12, Cites = 4)

6. A. Haakonsson, M.S. Madsen, R. Nielsen, A. Sandelin, S. Mandrup (2013) Acute genome-wide effects of Rosiglitazone on PPARγ transcriptional networks in adipocytes. Mol. Endocrinology, 27, 1536–1549 (DOI:10.1210/me.2013-1080, Cites = 0)

7. D. Neess, S. Bek, A.-B. Marcher, M. Bloksgaard, N. Færgeman, S. Mandrup (2013) Delayed hepatic adaptation to weaning in ACBP-/- mice is caused by disruption of the epidermal barrier. Cell Reports 5, 1403-1412.

8. M.S. Madsen, R. Siersbæk, M. Børgesen, R. Nielsen, S. Mandrup (2014) Peroxisome proliferator activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading. Mol. Cell. Biol. 34, 939-954.

9. R. Siersbæk, A. Rabiee, R. Nielsen, S. Sidoli, A. Loft, L.L.C. Poulsen, A. Rogowska-Wrzesinska, O.N. Jensen, S. Mandrup. Transcription factor cooperativity in early adipogenic hotspots and super-enhancers. Cell Reports, in press.

10. R. Siersbæk, S. Baek, A. Rabiee, R. Nielsen, S. Traynor, N. Clark, A. Sandelin, O.N. Jensen, M.-H. Sung, G.L. Hager, S. Mandrup. Molecular architecture of transcription factor hotspots in early adipogenesis. Cell Reports, in press