Jiri Lukas - Selected Publications#

152 research papers in peer reviewed journals; 41 review articles; 4 book chapters

TOTAL CITATIONS (Scopus.com; October, 2018): 32616
H-INDEX (Scopus.com; October, 2018): 92

CAREER TOP 10 PRIMARY PUBLICATIONS (all with JL as senior and/or corresponding author):

Somyajit, K., Gupta, R., Sedlackova, H., Neelsen, K. J., Ochs, F., Rask, M.-B., Choudhary, C. and Lukas, J.
Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science, 358, 797-802 (2017).

Ochs, F., Somyajit, K., Altmeyer, M., Rask, M-B., Lukas, J. and Lukas C.
53BP1 fosters fidelity of homology-directed DNA repair. Nature Structural and Molecular Biology, 23, 714-721 (2016).

Toledo, L., Altmeyer, M., Rask, M.-B., Lukas, C., Povlsen, L. K., Bekker-Jensen, S., Mailand, N., Bartek, J. and Lukas, J.
ATR shields replicating genomes against irreversible breakage by preventing global exhaustion of RPA. Cell, 155, 1088-1103 (2013).

Gudjonsson, T., Altmeyer, M., Savic, V., Toledo, L., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, S., Mailand, N., Neumann, B., Heriche, J.-K., Shearer, R., Saunders, D., Bartek, J., Lukas, J. and Lukas, C.
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell, 150, 607-709 (2012).

Lukas, C., Savic, V., Beker-Jensen, S., Doil, C., Neumann, B., Pedersen, R. S., Grofte, M., Chan, K. L., Hickson, I. D., Bartek, J. and Lukas, J.
53BP1 nuclear bodies shield DNA lesions generated by mitotic transmission of underreplicated chromosomes. Nature Cell Biology, 13, 243-253 (2011).

Doil, C., Mailand, N., Bekker-Jensen, S., Menard, P., Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, J. and Lukas, C.
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to promote accumulation of repair proteins. Cell 136, 435-446 (2009).

Mailand, N., Bekker-Jensen, S., Faustrup, H., Melander, F., Bartek, J., Lukas, C. and Lukas, J.
The RNF8 ubiquitin ligase promotes assembly of repair proteins at the DNA damage-modified chromatin. Cell 131, 887-900 (2007).

Lukas, C., Falck, J., Bartkova, J., Bartek, J. and Lukas, J.
Distinct spatio-temporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nature Cell Biology 5, 255-260 (2003).

Falck, J., Mailand, N., Syljuåsen, R. G., Bartek, J. and Lukas, J.
The Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410, 842-847 (2001).

Mailand, N., Falck, J., Lukas, C., Syljuåsen R., Welcker, M., Bartek, J. and Lukas, J.
Rapid destruction of human Cdc25A in response to DNA damage. Science 288, 1425-1429 (2000).