Xin Lu - Selected Publications#

Royer C, Sandham E, Slee E, Schneider F, Lagerholm CB, Godwin J, Veits N, Hathrell H, Zhou F, Leonavicius K, Garratt J, Narendra T, Vincent A, Jones C, Child T, Coward K, Graham C, Fritzsche M, Lu X [corresponding]], Srinivas S.
ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis.
Nature Commun. 2022 Feb 17;13(1):941. PMCID: PMC8854694.

Chen S, Wu JL, Liang Y, Tang YG, Song HX, Wu LL, Xing YF, Yan N, Li YT, Wang ZY, Xiao SJ, Lu X, Chen SJ, Lu M.
Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell. 2021 Feb 8;39(2):225-239.e8. PMID: 33357454.

Buti L, Ruiz-Puig C, Sangberg D, Leissing TM, Brewer RC, Owen RP, Sgromo B, Royer C, Ebner D, Lu X.
CagA-ASPP2 complex mediates loss of cell polarity and favors H. pylori colonization of human gastric organoids.
Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2645-2655. PMID: 31964836.

Chen S, Wu J, Zhong S, Li Y, Zhang P, Ma J, Ren J, Tan Y, Wang Y, Au KF, Siebold C, Bond GL, Chen Z, Lu M, Jones EY, Lu X.
iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.
Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17470-17479. PMID: 31395738.

Wang Y, Xiong H, Liu D, Hill C, Ertay A, Li J, Zou Y, Miller P, White E, Downward J, Goldin RD, Yuan X, Lu X.
Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells.
Autophagy. 2019 May;15(5):886-899. PMID: 30782064.

Owen RP, White MJ, Severson DT, Braden B, Bailey A, Goldin R, Wang LM, Ruiz-Puig C, Maynard ND, Green A, Piazza P, Buck D, Middleton MR, Ponting CP, Schuster-Böckler B, Lu X.

Single cell RNA-seq reveals profound transcriptional similarity between Barrett's oesophagus and oesophageal submucosal glands. Nature Commun. 2018 Oct 15;9(1):4261. PMID: 30323168.

Wang Y, Zhong S, Schofield CJ, Ratcliffe PJ, Lu X.
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively.
J Cell Sci. 2018 Nov 19;131(22):jcs219782. PMID: 30333145.

Dedeić Z, Sutendra G, Hu Y, Chung K, Slee EA, White MJ, Zhou FY, Goldin RD, Ferguson DJP, McAndrew D, Schneider JE, Lu X.
Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders.
Cell Death Differ. 2018 Jul;25(7):1289-1303. PMID: 29352264.

Lu M, Muers MR, Lu X.
Introducing STRaNDs: shuttling transcriptional regulators that are non-DNA binding.
Nature Rev Mol Cell Biol. 2016 Aug;17(8):523-32. PMID: 27220640.

Lu M, Zak J, Chen S, Sanchez-Pulido L, Severson DT, Endicott J, Ponting CP, Schofield CJ, Lu X.
A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.
Cell. 2014 May 22;157(5):1130-45. PMID: 24855949.

Full publication list

H-index: 57
Citations: 15,993