Tilman Grune - Selected Publications#

(h-factor: 97, total citation: 45716)

1. Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome. Grune T, Reinheckel T, Joshi M, Davies KJ. J Biol Chem. 1995 Feb 3;270(5):2344-51. (Citations: 465)

2. Comparative resistance of the 20S and 26S proteasome to oxidative stress. Reinheckel T, Sitte N, Ullrich O, Kuckelkorn U, Davies KJ, Grune T. Biochem J. 1998 Nov 1;335(Pt 3):637-42. (Citations: 476)

3. Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones. Ullrich O, Reinheckel T, Sitte N, Hass R, Grune T, Davies KJ. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6223-8. (Citations: 289)

4. Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II--aging of nondividing cells. Sitte N, Merker K, Von Zglinicki T, Davies KJ, Grune T. FASEB J. 2000 Dec;14(15):2503-10. (Citations: 200)

5. Hydrogen peroxide-induced structural alterations of RNAse A. Lasch P, Petras T, Ullrich O, Backmann J, Naumann D, Grune T. J Biol Chem. 2001 Mar 23;276(12):9492-502. (Citations: 114)

6. Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1. Grimm S, Ott C, Hörlacher M, Weber D, Höhn A, Grune T. Biochem J. 2012 Nov 15;448(1):127-39. (Citations: 91)

7. Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. Ott C, König J, Höhn A, Jung T, Grune T. Redox Biol. 2016 Dec;10:266-273. (Citations: 66)

8. Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP). Kehm R, Jähnert M, Deubel S, Flore T, König J, Jung T, Stadion M, Jonas W, Schürmann A, Grune T, Höhn A. Redox Biol. 2020 Oct;37:101748. (Citations: 4)

9. Accumulation of polyubiquitinated proteins: A consequence of early inactivation of the 26S proteasome. Reeg S, Castro JP, Hugo M, Grune T. Free Radic Biol Med. 2020 Nov 20;160:293-302 (Citations: 1)

10. Decreased proteasomal cleavage at nitrotyrosine sites in proteins and peptides. Ott C, Tomasina F, Campolo N, Bartesaghi S, Mastrogiovanni M, Leyva A, Batthyány C, Meinl W, Grune T, Radi R. Redox Biol. 2021 Oct;46:102106. (Citations: 3)

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