Patrik Brundin - Selected publications#

• Isacson O, Brundin P, Kelly PAT, Gage FH and Björklund A (1984) Functional neuronal replacement by grafted striatal neurons in ibotenic acid lesioned rat striatum. Nature 311: 458-460.
• Brundin P, Nilsson OG, Strecker RE, Lindvall O, Åstedt B and Björklund A (1986) Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease. Exp Brain Res 65: 235-240.
• Brundin P, Strecker RE, Widner H, Clarke DJ, Nilsson OG, Åstedt B, Lindvall O and Björklund A (1988) Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release. Exp Brain Res 70: 192-208.
• Lindvall O, Brundin P, Widner H, Rehncrona S, Gustavii B, Frackowiak R, Leenders KL, Sawle G, Rothwell JC, Marsden CD and Björklund A (1990) Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 247: 574-577.
• Wictorin K, Brundin P, Gustavii B, Lindvall O and Björklund A (1990) Reformation of long axonal pathways in adult rat central nervous system by human forebrain neuroblasts. Nature 347: 556-558.
• Grabowski M, Brundin P and Johansson BB (1993) Functional integration of cortical grafts in infarcted rat neocortex. Annal Neurol 34: 362-368.
• Nakao N, Frodl EM, Widner H, Carlson E, Eggerding FA, Epstein CJ and Brundin P (1995) Overexpressing Cu/Zn-superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nature Med 1: 226-231.
• Grasbon-Frodl EM, Nakao N, Lindvall O and Brundin P (1996).Phenotypic development of the human embryonic striatal primordium: a study of cultured and grafted neurons from the lateral and medial ganglionic eminences. Neuroscience 73: 171-183.
• Grasbon-Frodl EM, Andersson A and Brundin P (1996) Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion. J Neurochem 67: 1653-1660.
• Nakao N and Brundin P (1997) Effects of a-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid. Neuroscience 76: 749-761.
• Barkats M, Nakao N, Grasbon-Frodl EM, Biland-Bleuel A, Revah F, Mallet J and Brundin P (1997) Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase. Neuroscience 78: 703-713.
• Duan W-M, Widner H, Cameron RM and Brundin P (1998) Quinolinic acid-induced inflammation in the striatum does not impair the survival of neural allografts in the rat. Eur J Neurosc 10: 2595-2606.
• Schierle GS, Hansson O, Leist M, Nicotera P, Widner H and Brundin P (1999) Caspase inhibition reduces apoptosis and increases survival of nigral transplants. Nature Med 5: 97-100.
• Hansson O, Petersén Å, Leist M, Nicotera P, Castilho RF and Brundin P (1999) Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity. Proc Natl Acad Sci USA 96: 8727-8732.
• Schierle GS, Leist M, Martinou J-C, Widner H, Nicotera P and Brundin P (1999) Differential effects of Bcl-2 overexpression on fiber outgrowth and survival of embryonic dopaminergic neurons in intracerebral transplants. Eur J Neurosci 11: 3073-308.
• Piccini P, Brooks DJ, Bjorklund A, Gunn RN, Grasby PM, Rimoldi O, Brundin P, Hagell P, Rehncrona S, Widner H, Lindvall, O (1999) Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nature Neurosci 2:1137-1140.
• Brundin P, Pogarell O, Hagell P, Piccini P, Widner H, Schrag A, Kupsch A, Crabb L, Odin P, Gustavii B, Björklund A, Brooks DJ, David Marsden C, Oertel WH, Quinn NP, Rehncrona S and Lindvall O (2000) Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain 123: 1380-1390.
• Lotharius J, Barg S, Wiekop P, Lundberg C, Raymond HK, Brundin P (2002). Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. Journal of Biological Chemistry, in press.
• Hagell P, Piccini P, Björklund A, Brundin P, Rehncrona S, Widner H, Crabb L, Pavese N, Oertel WH, Quinn N, Brooks DJ, and Lindvall O (2002). Dyskinesias following neural transplantation in Parkinson's disease. Nature Neuroscience 5:627-628.