John van der Oost - Publications#

Statistics March 2019

• papers (peer reviewed): 289
  
• first authorships: 24
  
• last/corresponding authorships: 100
  
• H-index: 75 (Google scholar)
  
• number of citations: 25034 (Google scholar)
  
• papers (popular science): 3
  
• books/monographs: 5
  
• book chapters: 22
  
• patents: 25
  

Selected publications (2008-2019)

Brouns, S.J., Jore, M.M., Lundgren, M., Westra, E.R., Slijkhuis, R.J., Snijders, A.P., Dickman, M.J., Makarova, K.S., Koonin, E.V., Van der Oost*, J. (2008) Small CRISPR RNAs guide antiviral defense in prokaryotes. Science 321, 960-964

Westra, E.R., Van Erp, P.B.G., Wong, S.P., Künne, T., Seegers, C.L.C., Bollen, S., Jore, M.M., De Vos, W.M., Dame, R.T., De Vries, R., Brouns, S.J.J., Van der Oost*, J. (2012) CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3. Molecular Cell 46, 595-605

Swarts, D.C., Jore, M.M., Westra, E.R., Zhu, Y., Janssen, J.H., Snijders, A.P., Wang, Y., Patel, D.J., Berenguer, J., Brouns, S.J.J., Van der Oost*, J. (2014) DNA-guided DNA interference by a prokaryotic Argonaute. Nature 507, 258-261

Staals, R.H.J., Zhu, Y., Taylor, D.W., Kornfeld, J.E., Sharma, K., Barendregt, A., Vlot, M., Varossieau, K., Koehorst, J.J., Sakamoto, K., Suzuki, T., Dohmae, N., Yokoyama, S., Schaap, P.J., Urlaub, H., Heck, A.J.R., Nogales, E., Doudna, J.A., Shinkai, A., Van der Oost*, J. (2014) RNA-targeting by the Type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular Cell 56, 518–530

Swarts, D.C., Hegge, J.W., Hinojo, I., Shiimori, M., Ellis, M.A., Dumrongkulraksa, J., Terns, R.M., Terns, M.P., Van der Oost*, J. (2015) Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA. Nucleic Acids Research 43, 5120-5129

Mohanraju, P., Makarova, K., Zetsche, B., Zhang, F., Koonin, E., Van der Oost*, J. (2016) Diverse evolutionary roots and mechanistic variations of CRISPR-Cas systems. Science 353, pp. aad5147/1-12

Swarts, D.C., Szczepaniak, M., Sheng, G., Chandradoss, S.D., Zhu, Y., Timmers, E.M., Zhang, Y., Zhao, H., Lou, J., Wang, Y., Joo, C., Van der Oost*, J. (2017) Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute. Molecular Cell 65, 985-998

Zetsche, B., Heidenreich, M., Mohanraju, P., Fedorova, I., Kneppers, J., DeGennaro, E.M., Winblad, N., Choudhury, S.R., Abudayyeh, O.O., Gootenberg, J.S., Wu, W.Y., Scott, D.A., Severinov, K., Van der Oost*, J., Zhang*, F. (2017) Multiplex gene editing by CRISPR-Cpf1 by autonomous processing of a single crRNA array. Nature Biotechnology 35, 31-34.

Mougiakos, I., Mohanraju, P., Bosma, E.F., Finger Bou, M., Vrouwe, V., Nathutodi, M., Gussak, A., Brinkman, R.B., Van Kranenburg, R., Van der Oost*, J. (2017) Hot and sharp: Characterizing a thermo-stable Cas9 for bacterial genome editing and silencing. Nature Communications 8, 1647

Wu, W.Y., Lebbink, J.H.G., Kanaar, R., Geijsen, N., Van der Oost*, J. (2018) Genome editing by natural and engineered CRISPR-associated nucleases. Nature Chemical Biology 14, 642-651