Mihály Kovács - Selected Publications#

1. Harami GM, Pálinkás J, Seol Y, Kovács ZJ, Gyimesi M, Harami-Papp H, Neuman KC, Kovács M (2022): The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops. Nature Communications 3: 1-14.

2. Harami GM, Kovács ZJ, Pancsa R, Pálinkás J, Baráth V, Tárnok K, Málnási-Csizmadia A, Kovács M (2020): Phase separation by ssDNA binding protein controlled via protein−protein and protein−DNA interactions. Proc Natl Acad Sci USA 117: 26206-26217.

3. Gyimesi M, Horváth ÁI, Túrós D, Suthar SK, Pénzes M, Kurdi C, Canon L, Kikuti C, Ruppel KM, Trivedi DV, Spudich JA, Lőrincz I, Rauscher AÁ, Kovács M, Pál E, Komoly S, Houdusse A, Málnási-Csizmadia A (2020): Single residue variation in skeletal muscle myosin enables selective targeting: a small-molecule inhibitor ameliorates spastic gait disorder. Cell 183: 335-346.

4. Seol Y, Harami GM, Kovács M*, Neuman KC* (2019): Homology sensing via non-linear amplification of sequence dependent pausing by RecQ helicase. Elife 8: e45909.

5. Rauscher AÁ, Gyimesi M, Kovács M*, Málnási-Csizmadia A* (2018): Targeting myosin by blebbistatin derivatives: optimization and pharmacological potential. Trends Biochem. Sci. 43: 700-713.

6. Harami GM, Seol Y, In J, Ferencziová V, Martina M, Gyimesi M, Sarlós K, Kovács ZJ, Nagy NT, Sun Y, Vellai T, Neuman KC, Kovács M (2017): Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination. Proc Natl Acad Sci USA 114: E466-E475.

7. Ma X*, Kovács M*, Conti MA, Wang A, Zhang Y, Sellers JR, Adelstein RS (2012): Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci USA 109: 4509-14.

8. Kovács M, Thirumurugan K, Knight PJ, Sellers JR (2007): Load-dependent mechanism of non-muscle myosin 2. Proc. Natl. Acad. Sci. USA 104: 9994-9.

9. Kovács M, Tóth J, Hetényi C, Málnási-Csizmadia A, Sellers JR (2004): Mechanism of blebbistatin inhibition of myosin II. J. Biol. Chem. 279: 35557-63.

10. Kovács M, Wang F, Hu A, Zhang Y, Sellers JR (2003): Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform. J. Biol. Chem. 278: 38132-40.