Kenneth Harris - Curriculum Vitae#

PROFESSIONAL EXPERIENCE

• 2012 Professor of Quantitative Neuroscience, UCL Institute of Neurology
  
• 2011 - 2012 Professor of Neurotechnology, Imperial College London, UK
  
• 2009 - 2011 Reader in Neurotechnology, Imperial College London, UK
  
• 2009 Associate Professor, Center for Molecular and Behavioral Neuroscience (CMBN), Rutgers University, Newark NJ USA
  
• 2003 - 2009 Assistant Professor, CMBN, Rutgers University, Newark NJ USA
  
• 1999 - 2003 Postdoctoral Fellow, CMBN, Rutgers University, Newark NJ USA

EDUCATION

• 1995 - 1999 PhD in Neural Computation, University College London, UK. Thesis title: “Memory and Spatial Function in Animals and Robots”. Advisor: Dr. Michael Recce.
  
• 1992 - 1993 Certificate of Advanced Study, Mathematics, Cambridge University, UK. Thesis title: “A supersymmetric derivation of the Atiyah-Singer index theorem and Morse inequalities”. Advisor: Dr. Malcolm J. Perry
  
• 1989 - 1992 B.A. hons (1st Class), Mathematics, Cambridge University, UK

HONORS / AWARDS / POSITIONS

• 2019 ISI highly cited researcher
  
• 2017 - present Chair, Data Architecture Working Group, International Brain Lab
  
• 2012 Wolfson Research Merit Award, Royal Society
  
• 2005 Alfred P. Sloan Fellowship

SELECTED PUBLICATIONS

1. Bugeon S, … Harris KD (2022). A transcriptomic axis predicts state modulation of cortical interneurons. Nature. https://www.nature.com/articles/s41586-022-04915-7

2. Steinmetz NA, … Harris KD, Lee AK, Moser, EI, O’Keefe J, Renart A, Svoboda K, Hausser M, Haesler S, Carandini M, Harris TD (2021). Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings. Science. https://doi.org/10.1126/science.abf4588. https://www.biorxiv.org/content/10.1101/2020.10.27.358291v1

3. Peters AJ, Fabre JMJ, Steinmetz NA, Harris KD, Carandini M (2021). Striatal activity topographically reflects cortical activity. Nature. https://doi.org/10.1038/s41586-020-03166-8

4. Rossi LF, Harris KD, Carandini M (2020). Spatial connectivity matches direction selectivity in visual cortex. Nature 588, 648–652.

5. Qian X, Harris KD, Hauling T, Nicoloutsopoulos D, Manchado AM, Skene N, Hjerling-Leffler J, Nilsson M. (2019) Probabilistic cell typing enables fine mapping of closely related cell types in situ. Nature Methods 17(1): 101-106

6. Steinmetz NA, Zatka-Haas P Carandini M, Harris KD (2019). Distributed coding of choice, action, and engagement across the mouse brain. Nature 576(7786): 266-273.

7. Stringer C, Pachitariu M, Steinmetz NA, Carandini M, Harris KD (2019). High-dimensional geometry of visual cortical population activity. Nature 571(7765):361-365

8. Stringer C, Pachitariu M, Steinmetz NA, Reddy CB, Carandini M, Harris KD (2019). Spontaneous behaviors drive multidimensional, brainwide activity. Science 364(6437):255

9. Zeisel A, Hochgerner H, Lonnerberg P, Johnsson A, Memic F, van der Zwan J, Haring M, Braun E, Borm L, La Manno G, Codeluppi S, Furlan A, Skene N, Harris KD, Hjerling Leffler J, Arenas E, Ernfors P, Marklund U, Linnarsson S (2018). Molecular architecture of the mouse nervous system. Cell 174(4):999-1014.e22

10. Saleem AB, Diamanti EM, Fournier J, Harris KD, Carandini M (2018). Coherent representations of subjective spatial position in primary visual cortex and hippocampus. Nature 562(7725):124-127

11. Jun, J., Steinmetz, N.A., … Harris, K.D., Koch, C., O’Keefe, J., Harris, T.D. (2017). Fully integrated silicon probes for high-density recording of neural activity, Nature, 551: 232-236

12. Okun, M., Steinmetz, N., Cossell, L. Iacaruso, M.F., Ko, H., Bartho, P., Moore, T., Hofer, S., Mrsic-Flogel, T., Carandini, M., Harris, K.D. (2015) Diverse coupling of neurons to populations in sensory cortex. Nature, 521: 511-515.

13. Harris K.D., Mrsic-Flogel, T. (2013) Cortical connectivity and sensory coding. Nature, 503(7474): 51-8

14. Renart, A., de la Rocha, J., Bartho, P., Hollender, L., Parga, N., Reyes, A., Harris, K.D. (2010). The asynchronous state in cortical circuits. Science, 327(5965):587-90.

15. Harris, K.D., Csicsvari J., Hirase, H, Dragoi, G., Buzsaki G. (2003). Organization of cell assemblies in the hippocampus. Nature, 424:552-556.

16. Harris, K.D., Henze, D. A., Hirase, H, Leinekugel, X., Dragoi, G., Czurko, A. and Buzsáki, G. (2002). Spike train dynamics predicts theta-related phase precession in hippocampal pyramidal cells. Nature, 417: 738-741.

OPEN SOURCE ORIGINATING IN LAB (selected)

Vispy (https://vispy.org); Phy (https://github.com/cortex-lab/phy); Kilosort (https://github.com/cortex-lab/KiloSort); Suite2p (https://github.com/MouseLand/suite2p); Rigbox (https://github.com/cortex-lab/Rigbox); KlustaKwik (https://github.com/kwikteam/klusta); Probabilistic analysis of scRNA-seq data (https://github.com/cortex-lab/Transcriptomics); Gene detection for in situ transcriptomics (https://github.com/jduffield65/iss; Python version https://github.com/jduffield65/iss_python); Cell calling for in situ transcriptomics (https://github.com/acycliq/pciSeq);
In situ transcriptomics viewer (2d: https://github.com/acycliq/ca1; 3d: https://github.com/acycliq/3d_viewer)

RESEARCH GRANTS / FELLOWSHIPS (selected)

• 2022 - 2027 Brainwide organization of neuronal activity. £3,723,378, Wellcome Trust, jointly with M. Carandini
  
• 2022- 2025 Neuronal mechanisms of learning-evoked stimulus orthogonalization. £604,515, BBSRC, S. Failor researcher-co-investigator
  
• 2021 – 2024 Cellular resolution in situ transcriptomics of the mouse brain and Alzheimer's disease models. £864,514, MRC, jointly with K. Duff and B. de Strooper
  
• 2019 - 2024 International Brain laboratory. £10,000,000, Wellcome Trust; jointly with 20 other PIs
  
• 2018 - 2019 Probabilistic methods for cell classification. $126,097, Chan-Zuckerberg Initiative
  
• 2017 - 2019 International Brain laboratory. £1,998,000, Wellcome Trust; $3,938,750, Simons Foundation, jointly with 20 other PIs
  
• 2017 - 2021 Organization of large neuronal populations during behavior. £3,642,870. Wellcome Trust investigator award, jointly with M. Carandini
  
• 2017 - 2021 NEUROPOP: Large-scale analysis of neuronal population activity. €2,499,131. ERC Advanced Grant
  
• 2016 - 2020 Functional Neuromics of the Cerebral Cortex. £4,189,482.00. Wellcome Trust Strategic Award. Co-investigators M. Hausser, M. Carandini, W. Richardson, N. Kessaris, J. Hjerling-Leffler, M. Nilsson, P. Somogyi, S. Linnarsson
  
• 2014 - 2018 Disruption of large-scale neuronal activity patterns in Alzheimer's disease models. £103,327.00. MRC iCASE award, jointly with K. Phillips (Eli Lilly). £18,400 additional contribution from industrial partner
  
• 2014 - 2017 Global brain states and local cortical processing. Simons Collaboration on the Global Brain, $700,000, jointly with M. Carandini, UCL
  
• 2011 - 2016 Integration of internal and external signals in sensory cortex. £3,000,000. Wellcome investigator award, jointly with M. Carandini (UCL)
  
• 2010 - 2015 EPSRC Leadership Fellowship. “The neural marketplace.” £1,072,832