!!Austin Smith - Major publications \\ 1. __Smith AG__, Heath JK, Donaldson DD, Wong GG, Moreau J, Stahl M and Rogers D (1988) Inhibition of pluripotential embryonic stem cell . differentiation by purified polypeptides ''Nature'' 336: 688-690 \\ \\ 2. Niwa, H., Burdon, T., Chambers, l. and __Smith, A.G.__ (1998). Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. ''Genes and Development'' 12: 2048-2060. \\ \\ 3. Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D. Chambers, I., Scholer, H. and __Smith, A.G.__ (1998). Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct-4. ''Cell'' 95: 379-391. \\ \\ 4. Ying, Q.-L., Nichols, J., Evans, E.P. and __Smith, A.G.__ (2002). Changing potency by spontaneous fusion. ''Nature'' 416: 545-548 \\ \\ 5. Chambers, l., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S. and __Smith, A.G.__ (2003). Functional expression cloning of Nanog, a pluripotency sustaining factor in mouse embryonic stem cells. ''Cell'' 113: 643-655 \\ \\ 6. Ying, Q.-L., Nichols, J., Chambers, I., and __Smith, A.G.__ (2003). BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. ''Cell'' 115: 281-292 \\ \\ 7. Silva, J, Chambers, I, Pollard, S and __Smith, A.G.__ (2006). Nanog promotes transfer of pluripotency after cell fusion, ''Nature'' 441: 997-1001 \\ \\ 8. Chambers I, Silva J, Colby D, Nichols J, Robertson M, Nijmeijer B, Vrana J, Grotewold L, __Smith A.G.__ (2007) Nanog safeguards pluripotency and mediates germline development. ''Nature'' 450;1230—1234 \\ \\ 9. Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P. and __Smith A.__ (2008) The ground state of embryonic stem cell self- renewal ''Nature'' 453: 519-523 \\ \\ 10.SiIva J, Barrandon O, Nichols J, Kawaguchi J, Theunissen T and __Smith A.__ (2008) Promotion of reprogramming to ground state pluripotency by chemical inhibition ''PLoS Biology'' 6: e253