!!Pierre-Jean Corringer - Selected publications \\ 1- Prevost MS, Moraga-Cid G, Van Renterghem C, Edelstein J, Changeux JP, Corringer PJ\\ An intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proc Natl Acad Sci U S A. 110(42):17113-8 (2013)\\ \\ 2- Prevost MS, Delarue-Cochin S, Marteaux J, Colas C, Van Renterghem C, Blondel A, Malliavin T, Corringer PJ, Joseph D.\\ Identification of Cinnamic Acid Derivatives As Novel Antagonists of the Prokaryotic Proton-Gated Ion Channel GLIC.\\ J Med Chem. 56(11):4619-30 (2013)\\ \\ 3- Sauguet L, Howard R., Malherbe L. Lee U, Corringer P.J., R. Harris A., Delarue M.\\ Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.\\ Nat. Commun 16;4:1697 (2013)\\ \\ 4- Corringer PJ, Poitevin F, Prevost MS, Sauguet L, Delarue M, Changeux JP.\\ Structure and pharmacology of pentameric receptor channels: from bacteria to brain\\ Structure. 20:941-56. (2012) review\\ \\ 5- Prevost, MS, Sauguet, L., Nury H., Van Renterghem, C., Huon, C., Poitevin, F., Baaden, M., Delarue, M., Corringer, P.J.\\ A locally-closed conformation of a bacterial pentameric proton-gated ion channel\\ Nat Struct Mol Biol. 19:642-9 (2012) (Ranked 8 by Faculty of 1000)\\ \\ 6- Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P., Sonner, J.M., Delarue, M, Corringer, P.J.\\ X-ray structures of general anesthetics bound to a pentameric ligand-gated ion channel\\ Nature, 469:428-31 (2011) (Ranked 17 by Faculty of 1000)\\ \\ 7- Duret, C., Van Renterghem, C, Weng, Y, Prevost, MS, Moraga, G., Huon, C., Sonner, J.M., Corringer P.J.\\ A functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family\\ Proc Natl Acad Sci U S A. 108:12143-8 (2011) (Ranked 10 by Faculty of 1000)\\ \\ 8- Taly A, Corringer PJ, Guedin D, Lestage P, Changeux JP.\\ Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system.\\ Nat Rev Drug Discov. 8:733-50 (2009) review\\ \\ 9- Bocquet, N., Nury, H., Baaden, M., Le Poupon, C., Changeux, J.P., Delarue, M., Corringer, P.J.\\ X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation\\ Nature, 457 :111-4 (2009) (Ranked 14 by Faculty of 1000)\\ \\ 10- Bocquet, N., Prado de Carvalho, L., Cartaud, J., Neyton, J., Le Poupon, C., Taly, A., Grutter, T., Changeux, J.P., Corringer, P.J.\\ A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family\\ Nature, 445: 116-119 (2007)